PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Czasopismo
2009 | 4 | 1 | 65-70
Tytuł artykułu

Risk factors for breast cancer-related upper extremity lymphedema: Is immediate autologous breast reconstruction one of them?

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Breast cancer related upper extremity lymphedema (BCRL) reduces the quality of life of those who have had surgery for breast cancer. The aim of this study is to evaluate the risk factors for BCRL and determine whether immediate autologous tissue breast reconstruction is one of them. A case control study was conducted comparing patients with BCRL (n=97) to surgically treated breast cancer patients without BCRL (control, n=126). The groups were matched for age, type of breast surgery and radiation therapy. Postoperative upper extremity infection, body mass index (BMI), occupation (level of hand-use), and immediate autologous tissue breast reconstruction were investigated as a risk factor of BCRL. Mastectomy was performed on 47.6 % (n=60) and 37.2% (n=36) of patients in the control and the BCRL groups, respectively. Eight patients (13.3%) had immediate autologous tissue breast reconstruction in the control mastectomy group. Six of 36 BCRL patients (16.7%) underwent mastectomy with immediate autologous tissue breast reconstruction. There was no significant difference between groups with respect to incidence or method of immediate reconstruction (p=0.65). Patient occupation (level of hand use) was found to be positively correlated to development of BCRL (p=0.0001). Upper extremity infection rate was 22.7% in the BCRL group and 4.0% in the controls (p=0.0001). The mean BMI in the control and BCRL groups 26.8 kg/m2 and 29.1kg/m2, respectively (p=0.003). In conclusion, in this study characteristics positively associated with development of BCRL included occupation, infection, and increased BMI. Immediate reconstruction of the breast was not found as a risk factor for BCRL. However larger studies are needed, to further evaluate the effect of breast reconstruction on BCRL.
Wydawca

Czasopismo
Rocznik
Tom
4
Numer
1
Strony
65-70
Opis fizyczny
Daty
wydano
2009-03-01
online
2009-02-11
Twórcy
autor
  • Magee-Womens Hospital of the University of Pittsburgh, Medical Center Pittsburgh, Pittsburgh, PA, 15213, USA, akifserhatg@upmc.edu
autor
  • Magee-Womens Hospital of the University of Pittsburgh, Medical Center Pittsburgh, Pittsburgh, PA, 15213, USA
  • Magee-Womens Hospital of the University of Pittsburgh, Medical Center Pittsburgh, Pittsburgh, PA, 15213, USA
  • Magee-Womens Hospital of the University of Pittsburgh, Medical Center Pittsburgh, Pittsburgh, PA, 15213, USA
autor
  • Magee-Womens Hospital of the University of Pittsburgh, Medical Center Pittsburgh, Pittsburgh, PA, 15213, USA
  • Magee-Womens Hospital of the University of Pittsburgh, Medical Center Pittsburgh, Pittsburgh, PA, 15213, USA
  • Magee-Womens Hospital of the University of Pittsburgh, Medical Center Pittsburgh, Pittsburgh, PA, 15213, USA
autor
  • Magee-Womens Hospital of the University of Pittsburgh, Medical Center Pittsburgh, Pittsburgh, PA, 15213, USA
Bibliografia
  • [1] Nielsen I., Gordon S., Selby A., Breast cancer-related lymphoedema risk reduction advice: A challenge for health professionals, Cancer Treat. Rev., 2008, 34, 621–8 http://dx.doi.org/10.1016/j.ctrv.2007.11.002[WoS][Crossref]
  • [2] Helms G., Kühn T., Moser L., Remmel E., Kreienberg R., Shoulder-arm morbidity in patients with sentinel node biopsy and complete axillary dissection - data from a prospective randomised trial, Eur. J. Surg. Oncol., 2008, in press, DOI:10.1016/j.ejso.2008.06.013 [Crossref][WoS]
  • [3] Petrek J.A., Pressman P.I., Smith R.A., Lymphedema: current issues in research and management, CA Cancer J. Clin., 2000, 50, 292–307 http://dx.doi.org/10.3322/canjclin.50.5.292[Crossref]
  • [4] Erickson V.S., Pearson M.L., Ganz P.A., Adams J., Kahn K.L., Arm edema in breast cancer patients, J. Natl. Cancer Ins., 2001, 93, 96–111 http://dx.doi.org/10.1093/jnci/93.2.96[Crossref]
  • [5] Pressman P.I., Surgical treatment and lymphedema, Cancer, 1998, 83,12(Suppl.), 2782–7 http://dx.doi.org/10.1002/(SICI)1097-0142(19981215)83:12B+<2782::AID-CNCR26>3.0.CO;2-2[Crossref]
  • [6] Meek A.G., Breast radiotherapy and lymphedema, Cancer, 1998, 83,12(Suppl.), 2788–97 http://dx.doi.org/10.1002/(SICI)1097-0142(19981215)83:12B+<2788::AID-CNCR27>3.0.CO;2-I[Crossref]
  • [7] Mortimer P.S., The pathophysiology of lymphedema, Cancer, 1998, 83,12(Suppl.), 2798–802 http://dx.doi.org/10.1002/(SICI)1097-0142(19981215)83:12B+<2798::AID-CNCR28>3.0.CO;2-E[Crossref]
  • [8] Kissin M.W., Querci della Rovere G., Easton D., Westbury G., Risk of lymphedema following the treatment of breast cancer, Br. J. Surg., 1986, 73, 580–84 http://dx.doi.org/10.1002/bjs.1800730723[Crossref]
  • [9] Werner R.S., McCormick B., Petrek J., Cox L., Cirrincione C., Gray J.R., et al., Arm edema in conservatively managed breast cancer: Obesity is a major predictive factor, Radiology, 1991, 180, 177–84 [Crossref]
  • [10] Segerstrom K., Bjerle P., Graffman S., Nystrom A., Factors that influence the incidence of brachial edema after treatment of breast cancer, Scand. J. Plast. Recons. Hand Surg., 1992, 26, 223–7 http://dx.doi.org/10.3109/02844319209016016[Crossref]
  • [11] Mozes M., Papa M.Z., Karasik A., Reshef A., Adar R., The role of infection in postmastectomy lymphedema, Ann. Surg., 1982, 14, 73–83
  • [12] Soran A., D’Angelo G., Begovic M., Ardic F., Harlak A., Samuel Wieand H., et al., Breast cancer-related lymphedema-what are the significant predictors and how they affect the severity of lymphedema? Breast J., 2006, 12, 536–43 http://dx.doi.org/10.1111/j.1524-4741.2006.00342.x[Crossref]
  • [13] Sullivan S.R., Fletcher D.R., Isom C.D., Isik F.F., True incidence of all complications following immediate and delayed breast reconstruction, Plast. Reconstr. Surg., 2008, 122, 19–28 http://dx.doi.org/10.1097/PRS.0b013e3181774267[Crossref]
  • [14] Stillwell G.K., Treatment of postmastectomy lymphedema, Mod. Treatment, 1969, 6, 396–412
  • [15] Standard Occupational Classification 2000. Bureau of Labor Statistics http://www.bls.gov/SOC
  • [16] Johansson K., Ohlsson K., Ingvar C., Albertsson M., Ekdahl C., Factors associated with the development of arm lymphedema following breast cancer treatment: a match pair case-control study, Lymphology, 2002, 35, 59–71
  • [17] Fernandez J.C., Serin D., Bauges S., Fréquence des lymphoedemes du membre supérieur aprés traitement du cancer du sein. Facteurs du risque. A propos de 683 observations, Bull Cancer, 1996, 122, 536–41
  • [18] Mozes M., Papa M.Z., Karasik A., Reshef A., Adar R., The role of infection in postmastectomy lymphedema, Ann. Surg., 1982, 14, 73–83
  • [19] Woo P.C., Lum P.N., Wong S.S., Cheng V.C., Yuen K.Y., Cellulitis complicating lymphoedema, Eur. J. Clin. Microbiol. Infect. Dis., 2000, 19, 294–7 http://dx.doi.org/10.1007/s100960050478[Crossref]
  • [20] Brewer V.H., Hahn K.A., Rohrbach B.W., Bell J.L., Baddour L.M., Risk factor analysis for breast cellulitis complicating breast conservation therapy, Clin. Infect. Dis., 2000, 31, 654–9 http://dx.doi.org/10.1086/314021[Crossref]
  • [21] Hayes S.C., Janda M., Cornish B., Battistutta D., Newman B., Lymphedema after breast cancer: incidence, risk factors, and effect on upper body function, J. Clin. Oncol., 2008, 26, 3536–42 http://dx.doi.org/10.1200/JCO.2007.14.4899[Crossref][WoS]
  • [22] Suami H., Pan W.R., Taylor G.I., Changes in the lymph structure of the upper limb after axillary dissection: radiographic and anatomical study in a human cadaver, Plast. Reconstr. Surg., 2007, 120, 982–91 http://dx.doi.org/10.1097/01.prs.0000277995.25009.3e[Crossref][WoS]
  • [23] Deutsch M., Land S., Begovic M., Sharif S., The incidence of arm edema in women with breast cancer randomized on the National Surgical Adjuvant Breast and Bowel Project study B-04 to radical mastectomy versus total mastectomy and radiotherapy versus total mastectomy alone, Int. J. Radiat. Oncol. Biol. Phys., 2008, 70, 1020–4 [Crossref]
  • [24] Kronowitz S.J., Kuerer H.M., Hunt K.K., Ross M.I., Massey P.R., Ensor J.E., et al., Impact of sentinel lymph node biopsy on the evolution of breast reconstruction, Plast. Reconstr. Surg., 2006, 118, 1089–99 http://dx.doi.org/10.1097/01.prs.0000236794.73344.c4[Crossref]
  • [25] Jhaveri J.D., Rush S.C., Kostroff K., Derisi D., Farber L.A., Maurer V.E., et al., Clinical Outcomes of Postmastectomy Radiation Therapy after Immediate Breast Reconstruction, Int. J. Radiat. Oncol. Biol. Phys., 2008, 72, 859–865 [Crossref]
  • [26] Temple C.L., Strom E.A., Youssef A., Langstein H.N., Choice of recipient vessels in delayed TRAM flap breast reconstruction after radiotherapy, Plast. Reconstr. Surg., 2005, 115, 105–13
  • [27] Figus A., Ramakrishnan V., Rubino C., Hemodynamic changes in the microcirculation of DIEP flaps, Ann. Plast. Surg., 2008, 60, 644–8 http://dx.doi.org/10.1097/SAP.0b013e318145be31[Crossref]
  • [28] Heitland A.S., Markowicz M., Koellensperger E., Schoth F., Feller A.M., Pallua N., Duplex ultrasound imaging in free transverse rectus abdominis muscle, deep inferior epigastric artery perforator, and superior gluteal artery perforator flaps: early and long-term comparison of perfusion changes in free flaps following breast reconstruction, Ann. Plast. Surg., 2005, 55, 117–21 http://dx.doi.org/10.1097/01.sap.0000168690.00981.27[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11536-009-0010-0
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.