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2008 | 3 | 4 | 487-493
Tytuł artykułu

Sedation for middle ear surgery: prospective clinical trial comparing propofol and midazolam

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
During middle-ear-surgery under local anaesthesia (MES-LA), patients report hearing noises, feeling anxious, and experiencing earache. In a prospective randomized clinical trial, we compared propofol and midazolam for sedation in 68 patients scheduled for MES-LA. The starting dose of propofol was 1 to 1.5 mg per kilogram intravenously, followed by 1 to 2 mg per kilogram per hour given by infusion. The starting dose of midazolam was 0.02 to 0.05 mg per kilogram intravenously, followed by 0.01 to 0.02 mg per kilogram intravenously. Metamizol and fentanyl were added when required. Sedation was titrated to a Ramsay score of 3 to 4 and a bispectral index value of 70 to 80. Patients were assessed for vital parameters and sedation and pain scores. In the recovery room, readiness for discharge and satisfaction of both patient and surgeon with the procedure were assessed. The group receiving propofol had a significantly lower heart rate, shorter duration of sedation, and earlier readiness for discharge (p<0.05). There were no significant differences in other parameters evaluated. Seventy-nine per cent of patients in the group receiving propofol and 91.1% receiving midazolam would choose the same method of anaesthesia and sedation for any further MES-LA. Our results suggest that, compared to midazolam, propofol is more suitable for sedation in patients undergoing MES-LA. However, appropriate patient selection, adequate preparation, and careful monitoring are mandatory.
Wydawca

Czasopismo
Rocznik
Tom
3
Numer
4
Strony
487-493
Opis fizyczny
Daty
wydano
2008-12-01
online
2008-10-22
Twórcy
  • Department of Anaesthetics and Surgical Intensive Care, University Medical Centre Ljubljana, 1000, Ljubljana, Slovenia, janezbenedik@yahoo.com
  • Department of Anaesthetics and Surgical Intensive Care, University Medical Centre Ljubljana, 1000, Ljubljana, Slovenia
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11536-008-0069-z
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