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2008 | 3 | 4 | 521-524
Tytuł artykułu

Henoch-Schönlein purpura presenting with multiplex gastrointestinal manifestations and massive nephrotic syndrome in adulthood - a case report

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Henoch-Schönlein purpura (HSP) is a systemic small vessel vasculitis mainly affecting children. We report a case of a 49-year-old woman with severe gastrointestinal and renal involvement of HSP. Endoscopy revealed more characteristic findings in the terminal ileum than in the gastric antrum. Histological examinations of the biopsy samples from the ileum, antrum, skin and kidney confirmed the diagnosis of HSP. Parenteral corticosteroid therapy led to a rapid improvement of the gastrointestinal symptoms, but because of the excessive proteinuria intravenous cyclophosphamide therapy had to be introduced.
Wydawca

Czasopismo
Rocznik
Tom
3
Numer
4
Strony
521-524
Opis fizyczny
Daty
wydano
2008-12-01
online
2008-10-22
Twórcy
  • First Department of Internal Medicine, University of Szeged, H6720, Szeged, Hungary
autor
  • First Department of Internal Medicine, University of Szeged, H6720, Szeged, Hungary
  • Department of Pathology, University of Szeged, H6720, Szeged, Hungary
  • Department of Pathology, University of Szeged, H6720, Szeged, Hungary
autor
  • Department of Pathology, University of Szeged, H6720, Szeged, Hungary
autor
  • Department of Dermatology and Allergology, University of Szeged, H6720, Szeged, Hungary
  • First Department of Internal Medicine, University of Szeged, H6720, Szeged, Hungary
Bibliografia
  • [1] Tizard E.J., Henoch-Schönlein purpura, Arch. Dis. Child., 1999, 80, 380–383 http://dx.doi.org/10.1136/adc.80.4.380[Crossref]
  • [2] McKee P.H., Calonje E., Granter S.R., Pathology of the skin with clinical correlation, Elsevier Mosby, 2005, 1, 716–718
  • [3] Chen M.J., Wang T.E., Chang W.H. Tsai S.J., Liao W.S., Endoscopic findings in a patient with Henoch-Schönlein purpura, World J. Gastroenterol., 2005, 11, 2354–2356
  • [4] Sharma A., Wanchu A., Kalra N., Singh S., Bambery P., Successful treatment of severe gastrointestinal involvement in adult-onset Henoch-Schönlein purpura, Singapore Med. J., 2007, 48, 1047–1050 [PubMed]
  • [5] Karagozian R., Turbide C., Szilagyi A., Henoch-Schonlein purpura presenting with ileal involvement in an adult, Dig. Dis. Sci., 2004, 49, 1722–1726 http://dx.doi.org/10.1023/B:DDAS.0000043392.64347.ea[Crossref]
  • [6] Rieu P., Noel L.H., Henoch-Schönlein nephritis in children and adults. Morphological features and clinicopathological correlations, Ann. Med. Intern., 1999, 150, 151–159
  • [7] Shenoy M., Bradbury M.G., Lewis M.A., Webb N.J., Outcome of Henoch-Schönlein purpura nephritis treated with long-term immunosuppression, Pediatr. Nephrol., 2007, 22, 1717–1722 http://dx.doi.org/10.1007/s00467-007-0557-4[Crossref]
  • [8] de Almeida J.L., Campos L.M.A., Paim L.B., Leone C., Koch V.H., Silva C.A., Renal involvement in Henoch-Schönlein purpura: a multivariate analysis of initial prognostic factors, J. Pediatr., 2007, 83, 259–266 http://dx.doi.org/10.2223/JPED.1638[Crossref][WoS]
  • [9] Coppo R., Andrulli S., Amore A., Gianoglio B., Conti G., Peruzzi L., et al., Predictors of outcome in Henoch-Schönlein nephritis in chlidren and adults, Am. J. Kidney Dis., 2006, 47, 993–1003 http://dx.doi.org/10.1053/j.ajkd.2006.02.178[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11536-008-0060-8
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