PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Czasopismo
2008 | 3 | 4 | 475-481
Tytuł artykułu

Blood vessels of the normal and pathologically changed wall of the human vena saphena magna

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The vascular supply of the wall of human vena saphena magna was qualitatively studied by the use of several morphological methods on both normal and pathologically changed veins. The material was obtained from patients undergoing aortocoronary bypass or surgery of the varices, and material from cadavers. Under physiological conditions, the wall of vena saphena magna is supplied by delicate system of vasa vasorum, organized in a form of feeding vessels branched into an irregular loose adventitial mesh and continuing further as a microcirculatory network supplying the two outer thirds of the media. Small local dilatations and tortuosities of adventitial veins were found on heavy varicose veins. Slight increase of vasa vasorum growing into the innermost layer of media was detected, but the hyperplastic intima remained avascular. In patients with recurrent varices or with vein thrombophlebitis intimal hyperplasia, degradation of media and thrombosis, were found. Apparent massive increase of vasa vasorum growing into the whole media, hyperplastic intima and into the organizing thrombi, were regularly observed. The increase of vasa vasorum is a part of the complex of pathophysiological reactions of the vein wall on the hypoxia developing during the most serious pathological changes, and not as the primary varicogenic factor. The vascular supply of the wall of the human vena saphena magna was qualitatively studied by the use of several morphological methods on both normal and pathologically changed veins. The material was obtained from patients undergoing aortocoronary bypass grafting or surgery of varices, as well as materials from cadavers. Under physiological conditions the wall of vena saphena magna is supplied by a delicate system of vasa vasorum. It is organized in a form of feeding vessels branched into an irregular loose adventitial mesh, which continues further as a microcirculatory network supplying the outer two thirds of the media. Small local dilatations and tortuosities of adventitial veins were found on severe varicose veins. A slight increase of the vasa vasorum growing into the innermost layer of media was detected, but the hyperplastic intima remained avascular. In patients with recurrent varices or vein thrombophlebitis, intimal hyperplasia, degradation of media and thrombosis, were found. It was regularly observed that there was an apparent, massive increase of the vasa vasorum growing into the entire media, hyperplastic intima, and into the organizing thrombi. The increase of the vasa vasorum is due to the pathophysiological reaction of the vein wall as a result of hypoxia, which develops during the most serious pathological changes. The increase is not the primary varicogenic factor.
Wydawca
Czasopismo
Rocznik
Tom
3
Numer
4
Strony
475-481
Opis fizyczny
Daty
wydano
2008-12-01
online
2008-10-22
Twórcy
autor
autor
  • Surgical Department of the Regional Hospital in Ricany, 251 01, Ricany u Prahy, Czech Republic
  • Vascular and Muscle Research Unit, Department of Organismic Biology, University of Salzburg, 5020, Salzburg, Austria
  • Vascular and Muscle Research Unit, Department of Organismic Biology, University of Salzburg, 5020, Salzburg, Austria
  • Department of Pathology, Charles University in Prague, Praha, Czech Republic
autor
  • Department of Anatomy, Charles University in Prague, Praha, Czech Republic
  • Department of Cardiosurgery, Third Faculty of Medicine, Charles University in Prague, 100 00, Praha 10, Czech Republic
autor
  • Department of Cardiosurgery, Regional Hospital in Ceske Budejovice, 370 87, Ceske Budejovice, Czech Republic
Bibliografia
  • [1] Kachlik, D. Lametschwandtner, A., Rejmontová, J. Stingl, J., Vanek, I., Vasa vasorum of the human great saphenous vein, Surg. Radiol. Anat., 2002, 24, 377–381
  • [2] Kachlik D., Baca V., Stingl J., Sosna B., Lametschwandtner A., Minnich B., Setina M., Architectonic arrangement of the vasa vasorum of the human great saphenous vein, J Vasc Res, 2007, 44, 157–166 http://dx.doi.org/10.1159/000099142[Crossref][WoS]
  • [3] Kachlik D., Stingl J., Sosna B., Straka Z., Lametschwandtner A., Minnich B., Fara P., Morphological features of vasa vasorum in pathologically changed human great saphenous vein and its tributaries, VASA, 2008, 37 (2), 127–136. DOI:10.1024/0301-1526.37.2.127 http://dx.doi.org/10.1024/0301-1526.37.2.127[WoS][Crossref]
  • [4] Lametschwandtner A., Minnich B., Kachlik D., Setina M., Stingl J., Three-dimensional arrangement of the vasa vasorum in explanted segments of the aged human vena saphena magna: scanning electron microscopy and three-dimensional morphometry of vascular corrosion casts, Anat. Rec., 2004, 281A, 1372–1382 http://dx.doi.org/10.1002/ar.a.20098[Crossref]
  • [5] Kachlik D., Stingl J., Sosna B., Fara P., Lametschwandtner A., Minnich B., Straka Z., Morphological features of vasa vasorum of varicose human vena saphena magna. (Abstr. of 8th Congr. of Europ. Assoc. Clin. Anat., Palermo), Surg. Radiol. Anat. 2005, 27, SI 31
  • [6] Kachlik D., Stingl J., Sosna B., Fara P., Lametschwandtner A., Minnich B., Straka Z., (Abstr. of XXXI. Phlebol. Days, Prague), Prakt. Flebol. 2006, 15, 30
  • [7] Stingl J., Kachlik D., Sosna B., Fara P., Lametschwandtner A., Minnich B., Straka Z. Morphology of vasa vasorum in normal and varicose vena saphena magna. (Abstr. XXXI. Angiol. Days, Prague), Centr. Europ. Vasc. J., 2006, 5, 36
  • [8] Kachlik D., Baca V., Fara P., Lametschwandtner A.; Minnich B.; Sosna B.; Stingl J.; Straka Z.; Setina M. Blood supply of the wall of normal and varicose great saphenous vein, Prakt. flebol., 2006, 15, 90–94 (in Czech)
  • [9] Kachlik D., Baca V., Fara P., Lametschwandtner A., Minnich B., Sosna B., Stingl J., Straka Z., Setina M., Musil V., Anatomy of the vasa vasorum of the vena saphena magnain normal and pathological conditions, Erbetegsegek, 2007, 14, 117–122 (in Hungarian)
  • [10] Nicolaides N., Classification and grading of chronic venous disease in the lower limbs. A consensus statement, J. Cardiovasc. Surg., 1997, 37, 437–441.
  • [11] Cagiatti A., The saphenous venous compartment, Surg. Radiol. Anat., 1999, 21, 29–34 http://dx.doi.org/10.1007/BF01635049[Crossref]
  • [12] Biggel P., Taccoen A. Morphology and vascularization of the varicose great saphenous vein (Comparison to the normal structure). J. Mal. Vascul. (Paris), 1996, 21, 249–252 (in French)
  • [13] Crotty T. P., The path of retrograde flow from the lumen of the lateral saphenous vein of the dog into its vasa vasorum, Microvasc. Res., 1989, 37, 119–122 http://dx.doi.org/10.1016/0026-2862(89)90077-0[Crossref]
  • [14] Langes K., Hort W., Intimal fibrosis (phlebosclerosis in the saphenous vein of the lower limb: a quantitative analysis, Virchows Arch. A. Pathol. Anat., 1992, 421, 127–131 http://dx.doi.org/10.1007/BF01607045[Crossref]
  • [15] Haviarova Z., Weismann P., Durdik S., Kovac P., Stvrtinova V., Mraz P., Histomorphology of varicose veins. Prakt. flebol., 2005, 14, 12–15 (in Slovak)
  • [16] Michiels C., Bouaziz N., Remacle J., Role of the endothelium and blood stasis in the appearance of varicose veins, Int. Angiol., 2001, 21, 1–8 http://dx.doi.org/10.1159/000046212[Crossref]
  • [17] Lengyel I., Acsadi G., Histomorphological and pathobiochemical changes of varicose veins. A possible explanation of the development of varicosis, Acta Morphol. Hung., 1990, 38, 259–267 [PubMed]
  • [18] Curri B. S., The role of vasa vasorum in the genesis of varicose veins, Phlebologie (Paris) 1992, 20, 38–42
  • [19] Prokopova V., Kocova J., Horakova M., Treska V., Structure of the wall of the normal and varicose vein of the lower limb, Prakt. flebol., 1998, 7, 34–36 (in Czech)
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11536-008-0047-5
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.