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2008 | 3 | 2 | 123-133
Tytuł artykułu

Review of surfactin chemical properties and the potential biomedical applications

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Surfactin, a highly powerful biosurfactant produced by various strains of the genus Bacillus, exhibits antibacterial, antiviral, antitumor and hemolytic action. This anionic cyclic lipopeptide is constituted by a heptapeptide interlinked with a β-hydroxy fatty acid. Due to its amhipathic nature surfactin incorporates into the phospholipid bilayer and induces permeabilization and perturbation of target cells. The rising antibiotic resistance as well as a number of remarkable surfactin activities shows that it deserves special interest and is considered as a candidate compound for combating several health related issues. In this review, the current state of knowledge of surfactin properties, biomedical potential and limitations for its application is presented.
Wydawca

Czasopismo
Rocznik
Tom
3
Numer
2
Strony
123-133
Opis fizyczny
Daty
wydano
2008-06-01
online
2008-04-09
Twórcy
  • Department of Genetics and Microbiology, Faculty of Science, Charles University in Prague, 128 44, Praha 2, Czech Republic, gabina.sey@seznam.cz
  • Department of Genetics and Microbiology, Faculty of Science, Charles University in Prague, 128 44, Praha 2, Czech Republic
Bibliografia
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