PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Czasopismo
2012 | 10 | 2 | 533-537
Tytuł artykułu

A generic 3D kinetic model of gene expression

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Recent experiments show that mRNAs and proteins can be localized both in prokaryotic and eukaryotic cells. To describe such situations, I present a 3D mean-field kinetic model aimed primarily at gene expression in prokaryotic cells, including the formation of mRNA, its translation into protein, and slow diffusion of these species. Under steady-state conditions, the mRNA and protein spatial distribution is described by simple exponential functions. The protein concentration near the gene transcribed into mRNA is shown to depend on the protein and mRNA diffusion coefficients and degradation rate constants.
Wydawca

Czasopismo
Rocznik
Tom
10
Numer
2
Strony
533-537
Opis fizyczny
Daty
wydano
2012-04-01
online
2012-03-31
Bibliografia
  • [1] M. Kaern, T.C. Elston, W.J. Blake, J.J. Collins, Nature Rev. Genet. 6, 451 (2005) http://dx.doi.org/10.1038/nrg1615[Crossref]
  • [2] J. Paulsson, Phys. Life Rev. 2, 157 (2005) http://dx.doi.org/10.1016/j.plrev.2005.03.003[Crossref]
  • [3] J. Rausenberger, C. Fleck, J. Timmer, M. Kollmann, Progr. Biophys. Molec. Biol. 100, 57 (2009) http://dx.doi.org/10.1016/j.pbiomolbio.2009.06.003[Crossref]
  • [4] A.S. Ribeiro, Math. Biosci. 223, 1 (2010) http://dx.doi.org/10.1016/j.mbs.2009.10.007[Crossref]
  • [5] G. Tiana, S. Krishna, S. Pigolotti, M.H. Jensen, K. Sneppen, Phys. Biol. 4, R1 (2007) http://dx.doi.org/10.1088/1478-3975/4/2/R01[Crossref]
  • [6] O. Purcell, N.J. Savery, C.S. Grierson, M. di Bernardo, J. Roy. Soc. Interface 7, 1503 (2010) http://dx.doi.org/10.1098/rsif.2010.0183[Crossref]
  • [7] V.P. Zhdanov, Phys. Rep. 500, 1 (2011) http://dx.doi.org/10.1016/j.physrep.2010.12.002[Crossref]
  • [8] U. Alon, Nature Rev. Genet. 8, 450 (2007) http://dx.doi.org/10.1038/nrg2102[Crossref]
  • [9] G. Karlebach, R. Shamir, Nature Rev. Molec. Cell Biol. 9, 771 (2008)
  • [10] M.C. Lagomarsino, B. Bassetti, G. Castellani, D. Remondini, Molec. Biosyst. 5, 335 (2009) http://dx.doi.org/10.1039/b816841p[Crossref]
  • [11] D.F.T. Veiga, B. Dutta, G. Balazsi, Molec. Biosyst. 6, 469 (2010) http://dx.doi.org/10.1039/b916989j[Crossref]
  • [12] M. Valencia-Burtona, et al., Proc. Natl. Acad. Sci. USA 106, 16399 (2009) http://dx.doi.org/10.1073/pnas.0907495106[Crossref]
  • [13] J.H. Russell, K.C. Keiler, Proc. Natl. Acad. Sci. USA 106, 16405 (2009) http://dx.doi.org/10.1073/pnas.0904904106[Crossref]
  • [14] P. Montero Llopis, et al., Nature 466, 77 (2010) http://dx.doi.org/10.1038/nature09152[Crossref]
  • [15] K. Nevo-Dinur, A. Nussbaum-Shochat, S. Ben-Yehuda, O. Amster-Choder, Science 331, 1081 (2011) http://dx.doi.org/10.1126/science.1195691[Crossref]
  • [16] D.Z. Rudner, R. Losick, Cold Spring Harb. Perspect. Biol. 2, a000307 (2010) http://dx.doi.org/10.1101/cshperspect.a000307[Crossref]
  • [17] E. Evguenieva-Hackenberg, V. Roppelt, C. Lassek, G. Klug, RNA Biol. 8, 49 (2011) http://dx.doi.org/10.4161/rna.8.1.14066[Crossref]
  • [18] N.E. Broude, Molec. Microbiol. 80, 1137 (2011) http://dx.doi.org/10.1111/j.1365-2958.2011.07652.x[Crossref]
  • [19] K.C. Keiler, Curr. Opin. Microbiol. 14, 155 (2011) http://dx.doi.org/10.1016/j.mib.2011.01.009[Crossref]
  • [20] J.T. Mika, B. Poolman, Curr. Opin. Biotechnol. 22, 117 (2011) http://dx.doi.org/10.1016/j.copbio.2010.09.009[Crossref]
  • [21] S.A. Isaacson, C.S. Peskin, SIAM J. Sci. Comp. 28, 47 (2006) http://dx.doi.org/10.1137/040605060[Crossref]
  • [22] V.P. Zhdanov, JETP Lett. 85, 302 (2007) http://dx.doi.org/10.1134/S0021364007060082[Crossref]
  • [23] V.P. Zhdanov, Chem. Phys. Lett. 458, 247 (2008) http://dx.doi.org/10.1016/j.cplett.2008.03.047[Crossref]
  • [24] V.P. Zhdanov, Biophys. Rev. Lett. 4, 267 (2009) http://dx.doi.org/10.1142/S1793048009001034[Crossref]
  • [25] Q. Ma, G. Shi, S. Xu, Y. Zou, Neural Comput. Applic. 20, 507 (2011) http://dx.doi.org/10.1007/s00521-011-0575-9[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11534-012-0011-5
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.