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2011 | 9 | 5 | 1366-1371
Tytuł artykułu

Interplay of viral miRNAs and host mRNAs and proteins

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Recent experiments indicate that several viruses may encode microRNAs (miRNAs) in cells. Such RNAs may interfere with the host mRNAs and proteins. We present a kinetic analysis of this interplay. In our treatment, the viral miRNA is considered to be able to associate with the host mRNA with subsequent degradation. This process may result in a decline of the mRNA population and also in a decline of the population of the protein encoded by this mRNA. With these ingredients, we first show the types of the corresponding steady-state kinetics in the cases of positive and negative regulation of the miRNA synthesis by the protein. In addition, we scrutinize the situation when the protein regulates the virion replication or, in other words, provides a feedback for the replication. For the negative feedback, the replication rate is found to increase with increasing the intracellular virion population. For the positive feedback, the replication rate first increases and then drops. These features may determine the stability of steady states.
Wydawca

Czasopismo
Rocznik
Tom
9
Numer
5
Strony
1366-1371
Opis fizyczny
Daty
wydano
2011-10-01
online
2011-09-15
Bibliografia
  • [1] J. Mercer, M. Schelhaas, A. Helenius, Annu. Rev. Biochem. 79, 803 (2010) http://dx.doi.org/10.1146/annurev-biochem-060208-104626[Crossref]
  • [2] Q. Sattentau, Nature Rev. Microbiol. 6, 815 (2008) http://dx.doi.org/10.1038/nrmicro1972[Crossref]
  • [3] A.S. Perelson, Nature. Rev. Immun. 2, 28 (2002) http://dx.doi.org/10.1038/nri700[Crossref]
  • [4] S.M. Andrew, C.T.H. Baker, G.A. Bocharov, J. Comput. Appl. Math. 205, 669 (2007) http://dx.doi.org/10.1016/j.cam.2006.03.035[Crossref]
  • [5] R. Xu, Z. Ma, J. Theor. Biol. 257, 499 (2009) http://dx.doi.org/10.1016/j.jtbi.2009.01.001[Crossref]
  • [6] A.L. Bauer, C.A.A. Beauchemin, A.S. Perelson, Inform. Sci. 179, 1379 (2009) http://dx.doi.org/10.1016/j.ins.2008.11.012[Crossref]
  • [7] V.P. Zhdanov, JETP Lett. 93, 551 (2011) http://dx.doi.org/10.1134/S0021364011090153[Crossref]
  • [8] R. Srivastava, L. You, J. Summers, J. Yin, J. Theor. Biol. 218, 309 (2002) http://dx.doi.org/10.1006/jtbi.2002.3078[Crossref]
  • [9] V.P. Zhdanov, J. Phys. A: Math. Gen. 37, L63 (2004) http://dx.doi.org/10.1088/0305-4470/37/5/L03[Crossref]
  • [10] V.P. Zhdanov, Phys. Biolog. 2, 46 (2005) http://dx.doi.org/10.1088/1478-3967/2/1/006[Crossref]
  • [11] V.P. Zhdanov, BioSystems 97, 117 (2009) http://dx.doi.org/10.1016/j.biosystems.2009.05.005[Crossref]
  • [12] B. Reddy, J. Yin, AIDS Res. Human Retrovir. 15, 273 (1999) http://dx.doi.org/10.1089/088922299311457[Crossref]
  • [13] Y. Sidorenko, U. Reichl, Biotech. Bioing. 88, 1 (2004) http://dx.doi.org/10.1002/bit.20096[Crossref]
  • [14] Y. Sidorenko, J. Schulze-Horsel, A. Voigt, U. Reichl, A. Kienle, Chem. Eng. Sci. 63, 157 (2008) http://dx.doi.org/10.1016/j.ces.2007.09.014[Crossref]
  • [15] Y. Sidorenko, A. Voigt, J. Schulze-Horsel, U. Reichl, A. Kienle, Chem. Eng. Sci. 63, 2299 (2008) http://dx.doi.org/10.1016/j.ces.2007.12.034[Crossref]
  • [16] J. Yin, AICHE J. 53, 2202 (2007) http://dx.doi.org/10.1002/aic.11263[Crossref]
  • [17] J. Sardanyes, R.V. Sole, S.F. Elena, J. Virol. 83, 12579 (2009) http://dx.doi.org/10.1128/JVI.00767-09[Crossref]
  • [18] E.L. Haseltine, J.B. Rawlings, J. Yin, Comput. Chem. Eng. 29, 675 (2005) http://dx.doi.org/10.1016/j.compchemeng.2004.08.022[Crossref]
  • [19] T.R. Mercer, M.E. Dinger, J.S. Mattick, Nature Rev. Genet. 10, 155 (2009) http://dx.doi.org/10.1038/nrg2521[Crossref]
  • [20] C.P. Ponting, P.L. Oliver, W. Reik, Cell 136, 629 (2009) http://dx.doi.org/10.1016/j.cell.2009.02.006[Crossref]
  • [21] J.E. Wilusz, H. Sunwoo, D.L. Spector, Gen. Devel. 23, 1494 (2009) http://dx.doi.org/10.1101/gad.1800909[Crossref]
  • [22] D.P. Bartel, Cell 136, 215 (2009) http://dx.doi.org/10.1016/j.cell.2009.01.002[Crossref]
  • [23] M. Ghildiyal, P.D. Zamore, Nature Rev. Genet. 10, 94 (2009) http://dx.doi.org/10.1038/nrg2504[Crossref]
  • [24] V.N. Kim, J. Han, M.C. Siomi, Nature Rev. Molec. Cell. Biol. 10, 126 (2009) http://dx.doi.org/10.1038/nrm2632[Crossref]
  • [25] E. Gottwein, B. R. Cullen, Cell Host Micr. 3, 375 (2008) http://dx.doi.org/10.1016/j.chom.2008.05.002[Crossref]
  • [26] Z. Ghosh, B. Mallick, J. Chakrabarti, Nucl. Acids Res. 37, 1035 (2009) http://dx.doi.org/10.1093/nar/gkn1004[Crossref]
  • [27] R.L. Skalsky, B.R. Cullen, Annu. Rev. Microbiol. 64, 123 (2010) http://dx.doi.org/10.1146/annurev.micro.112408.134243[Crossref]
  • [28] C.C. Xiao, K. Rajewsky, Cell 136, 26 (2009) http://dx.doi.org/10.1016/j.cell.2008.12.027[Crossref]
  • [29] V.S. Mahajan, A. Drake, J.Z. Chen, Trends Immun. 30, 1 (2008) http://dx.doi.org/10.1016/j.it.2008.08.009[Crossref]
  • [30] V.P. Zhdanov, Phys. Rep. 500, 1 (2011) http://dx.doi.org/10.1016/j.physrep.2010.12.002[Crossref]
  • [31] V.P. Zhdanov, J. Phys. A: Math. Theor. 41, 285101 (2008) http://dx.doi.org/10.1088/1751-8113/41/28/285101[Crossref]
  • [32] V.P. Zhdanov, Biosystems 95, 75 (2009) http://dx.doi.org/10.1016/j.biosystems.2008.07.002[Crossref]
  • [33] V.P. Zhdanov, JETP Lett. 88, 466 (2008) http://dx.doi.org/10.1134/S0021364008190120[Crossref]
  • [34] J.R. Chubb, T.B. Liverpool, Curr. Opin. Genet. Develop. 20, 478 (2010) http://dx.doi.org/10.1016/j.gde.2010.06.009[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11534-011-0054-z
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