PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Czasopismo
2011 | 9 | 4 | 898-908
Tytuł artykułu

Effect of cytoskeletal element degradation on merging of concentration waves in slow axonal transport

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The aim of this paper is to investigate, by means of a numerical simulation, the effect of the half-life of cytoskeletal elements (CEs) on superposition of several waves representing concentrations of running, pausing, and off-track anterograde and retrograde CE populations. The waves can be induced by simultaneous microinjections of radiolabeled CEs in different locations in the vicinity of a neuron body; alternatively, the waves can be induced by microinjecting CEs at the same location several times, with a time interval between the injections. Since the waves spread out as they propagate downstream, unless their amplitude decreases too fast, they eventually superimpose. As a result of superposition and merging of several waves, for the case with a large half-life of CEs, a single wave is formed. For the case with a small half-life the waves vanish before they have enough time to merge.
Wydawca

Czasopismo
Rocznik
Tom
9
Numer
4
Strony
898-908
Opis fizyczny
Daty
wydano
2011-08-01
online
2011-04-30
Twórcy
  • Dept. of Mechanical and Aerospace Engineering, North Carolina State University, Campus Box 7910, Raleigh, NC, 27695-7910, USA, avkuznet@eos.ncsu.edu
  • Institute of Engineering Thermophysics, National Academy of Sciences, Kiev, Ukraine
  • Institute of Engineering Thermophysics, National Academy of Sciences, Kiev, Ukraine
Bibliografia
  • [1] S. Sasaki, H. Warita, K. Abe, M. Iwata, Acta Neuropathol. 110, 48 (2005) http://dx.doi.org/10.1007/s00401-005-1021-9[Crossref]
  • [2] J.P. Julien, Cell104, 581 (2001) http://dx.doi.org/10.1016/S0092-8674(01)00244-6[Crossref]
  • [3] A. Brown, Nat. Rev. Mol. CellBiol. 1, 153 (2000) http://dx.doi.org/10.1038/35040102[Crossref]
  • [4] R.B. Vallee, G.S. Bloom, Annu. Rev. Neurosci. 14, 59 (1991) http://dx.doi.org/10.1146/annurev.ne.14.030191.000423[Crossref]
  • [5] S. Roy et al., J. Neurosci. 27, 3131 (2007) http://dx.doi.org/10.1523/JNEUROSCI.4999-06.2007[Crossref]
  • [6] A. Brown, L. Wang, P. Jung, Mol. Biol. Cell 16, 4243 (2005) http://dx.doi.org/10.1091/mbc.E05-02-0141[Crossref]
  • [7] G. Craciun, A. Brown, A. Friedman, J. Theor. Biol. 237, 316 (2005) http://dx.doi.org/10.1016/j.jtbi.2005.04.018[Crossref]
  • [8] N. Trivedi, P. Jung, A. Brown, J. Neurosci. 27, 507 (2007) http://dx.doi.org/10.1523/JNEUROSCI.4227-06.2007[Crossref]
  • [9] Y. He et al., J. CellBiol. 168, 697 (2005) http://dx.doi.org/10.1083/jcb.200407191[Crossref]
  • [10] J.V. Shah, L.A. Flanagan, P.A. Janmey, J.F. Leterrier, Mol. Biol. Cell 11, 3495 (2000) [PubMed]
  • [11] O.I. Wagner et al., Mol. Biol. Cell 15, 5092 (2004) http://dx.doi.org/10.1091/mbc.E04-05-0401[Crossref]
  • [12] J.T. Yabe, A. Pimenta, T.B. Shea, J. Cell Sci. 112, 3799 (1999)
  • [13] C.W. Jung et al., Mol. Brain. Res. 141, 151 (2005) http://dx.doi.org/10.1016/j.molbrainres.2005.08.009[Crossref]
  • [14] J. Niclas, F. Navone, N. Hombooher, R.D. Vale, Neuron 12, 1059 (1994) http://dx.doi.org/10.1016/0896-6273(94)90314-X[Crossref]
  • [15] C.H. Xia, A. Rahman, Z.H. Yang, L.S.B. Goldstein, Genomics 52, 209 (1998) http://dx.doi.org/10.1006/geno.1998.5427[Crossref]
  • [16] F. Navone et al., J. Cell Biol. 117, 1263 (1992) http://dx.doi.org/10.1083/jcb.117.6.1263[Crossref]
  • [17] A. Uchida, N.H. Alami, A. Brown, Mol. Biol. Cell 20, 4997 (2009) http://dx.doi.org/10.1091/mbc.E09-04-0304[Crossref]
  • [18] C.S. Mitchell, R.H. Lee, J. Theor. Biol. 257, 430 (2009) http://dx.doi.org/10.1016/j.jtbi.2008.12.011[Crossref]
  • [19] P. Jung, A. Brown, Phys. Biol. 6, 046002 (2009) http://dx.doi.org/10.1088/1478-3975/6/4/046002[Crossref]
  • [20] A.V. Kuznetsov, A.A. Avramenko, D.G. Blinov, International Journal for Numerical Methods in Biomedical Engineering, DOI:10.1002/cnm.1417 (in press) [Crossref]
  • [21] S. Millecamps et al., J. Neurosci. 27, 4947 (2007) http://dx.doi.org/10.1523/JNEUROSCI.5299-06.2007[Crossref]
  • [22] A.V. Kuznetsov, A.A. Avramenko, D.G. Blinov, Int. Com- mun. Heat Mass Transfer 36, 641 (2009) http://dx.doi.org/10.1016/j.icheatmasstransfer.2009.04.002[Crossref]
  • [23] A. Yuan et al., J. Neurosci. 29, 11316 (2009) http://dx.doi.org/10.1523/JNEUROSCI.1942-09.2009[Crossref]
  • [24] M.V. Rao et al., J. Cell Biol. 159, 279 (2002) http://dx.doi.org/10.1083/jcb.200205062[Crossref]
  • [25] A. Friedman, B. Hu, Arch. Ration. Mech. Anal. 186, 251 (2007) http://dx.doi.org/10.1007/s00205-007-0069-1[Crossref]
  • [26] J.A. Galbraith, T.S. Reese, M.L. Schlief, P.E. Gallant, Proc. Nat. Acad. Sci. U.S.A. 96, 11589 (1999) http://dx.doi.org/10.1073/pnas.96.20.11589[Crossref]
  • [27] B.P. Graham, K. Lauchlan, D.R. Mclean, J. Comput. Neurosci. 20, 43 (2006) http://dx.doi.org/10.1007/s10827-006-5330-3[Crossref]
  • [28] J. Alvarez, A. Giuditta, E. Koenig, Prog. Neurobiol. 62, 1 (2000) http://dx.doi.org/10.1016/S0301-0082(99)00062-3[Crossref]
  • [29] K.E. Miller, D.C. Samuels, J. Theor. Biol. 186, 373 (1997) http://dx.doi.org/10.1006/jtbi.1996.0355[Crossref]
  • [30] R.A. Nixon, K.B. Logvinenko, J. Cell Biol. 102, 647 (1986) http://dx.doi.org/10.1083/jcb.102.2.647[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11534-010-0116-7
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.