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2013 | 11 | 12 | 2144-2150
Tytuł artykułu

Stereoselective preparation of mono- and bis-derivatives of pentacyclo[6.3.0.02,6.03,10.05,9] undecane (D 3-trishomocubane)

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The rearrangement of easily accessible Cookson’s diketone with chlorosulfonic acid in chloroform followed by the acidic hydrolysis gave 6-chloro-7-hydroxy-dichloropentacyclo[6.3.0.02,6.03,10.05,9]undecane-4-one, whose syn-stereochemistry was assigned through the X-ray crystal structure analysis. This key structure was used for the stereoselective synthesis of the D 3-trishomocubane derivatives as well as for the preparation of potential drugs bearing hydroxy- and amino-functional groups. A new multigram preparative synthesis of D 3-trishomocubane was developed. [...]
Wydawca

Czasopismo
Rocznik
Tom
11
Numer
12
Strony
2144-2150
Opis fizyczny
Daty
wydano
2013-12-01
online
2013-09-26
Twórcy
  • Department of Organic Chemistry, Kiev Polytechnic Institute, 03056, Kiev, Ukraine
  • Department of Organic Chemistry, Kiev Polytechnic Institute, 03056, Kiev, Ukraine
  • Department of Organic Chemistry, Kiev Polytechnic Institute, 03056, Kiev, Ukraine
  • Department of Organic Chemistry, Kiev Polytechnic Institute, 03056, Kiev, Ukraine
  • Institute of Organic Chemistry, Justus-Liebig University, D-35392, Giessen, Germany
autor
  • Department of Organic Chemistry, Kiev Polytechnic Institute, 03056, Kiev, Ukraine
  • Department of Organic Chemistry, Kiev Polytechnic Institute, 03056, Kiev, Ukraine, vnr@xtf.kpi.ua
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11532-013-0339-8
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