PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Czasopismo
2013 | 11 | 10 | 1699-1709
Tytuł artykułu

Antioxidant and chemical properties of Inula helenium root extracts

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The objective of the paper was to investigate the chemical composition of Inula helenium roots extracts and to evaluate the antioxidant potential conferred by the chemical constituents. GC/MS and HPLC/MS techniques were used to characterize two extracts separated from Inula helenium roots by extraction with chloroform and ethyl acetate, respectively. Volatile compounds have been identified by GC from their mass spectra and retention time values, while HPLC identification of phenolic compounds was realized by comparing their retention times, UV and MS spectra with those of standards or literature data. Measurements of antioxidant activity of Inula helenium root extracts showed a variation between them, which can be correlated with the flavonoid and total phenolic contents. Both Inula helenium root extracts contain phenolic acids (caffeic, chlorogenic, dicaffeoyl quinic, hydroxibenzoic), terpenes (alantolactone) and different flavonoids (epicatechin, catechin gallate, ferulic acid-4-O-glucoside, dihydroquercetin pentosyl rutinoside, kaempherol-7-O-dipentoside, quercetin-3-O-β-glucopyranoside). In addition, the study provides preliminary data on the anti-inflammatory activity of Inula helenium root extracts, this being evaluated using the fresh egg albumin as phlogistic agent, and aspirin as reference compound. Root extracts of I. helenium did not exert any significant anti-inflammatory effect on egg albumin-induced rat paw edema. [...]
Wydawca

Czasopismo
Rocznik
Tom
11
Numer
10
Strony
1699-1709
Opis fizyczny
Daty
wydano
2013-10-01
online
2013-07-19
Twórcy
  • Department of Natural Polymers, “Petru Poni” Institute of Macromolecular Chemistry, Romanian Academy, Iasi, 700487, Romania
  • Agricultural Sciences and Veterinary Medicine University, Iasi, 700490, Romania
  • Oenological Research Center, Romanian Academy, Iasi, 700490, Romania
  • Department of Natural Polymers, “Petru Poni” Institute of Macromolecular Chemistry, Romanian Academy, Iasi, 700487, Romania
autor
  • National Institute for Chemical Pharmaceutical Research and Development, Bucuresti, 031299, Romania
  • Department of Natural Polymers, “Petru Poni” Institute of Macromolecular Chemistry, Romanian Academy, Iasi, 700487, Romania, cateaca14@yahoo.com
  • Department of Natural Polymers, “Petru Poni” Institute of Macromolecular Chemistry, Romanian Academy, Iasi, 700487, Romania
Bibliografia
  • [1] A. Stojakowska, J. Malarz, S. Zubek, K. Turnau, W. Kisiel, Biochem. System. Ecol. 38, 232 (2010) http://dx.doi.org/10.1016/j.bse.2009.12.011[Crossref]
  • [2] J. Zhao, Y. Li, Q. Liu, K. Gao, Food Chem. 120, 512 (2010) http://dx.doi.org/10.1016/j.foodchem.2009.10.045[Crossref]
  • [3] T. Konishi, Y. Shimada, T. Nagao, H. Okabe, T. Konoshima, Biol. Pharm. Bull. 25, 1370 (2002) http://dx.doi.org/10.1248/bpb.25.1370[Crossref]
  • [4] Z. Stojanović-Radić, Lj. Čomić, N. Radulović, P. Blagojević, M. Denić, A. Miltojević, J. Rajković, T. Mihajilov-Krstev, Eur. J. Clin. Microbiol. Infect. Dis. 31, 015 (2012)
  • [5] N. J. Lawrence, A.T. McGown, J. Nduka, J.A. Hadfield, R.G. Pritchard, Bioorg. Med. Chem. Lett. 11, 429 (2001) http://dx.doi.org/10.1016/S0960-894X(00)00686-7[Crossref]
  • [6] C.-N. Chen, H.-H. Huang, C.-L. Wu, P. C. Coney Lin, J.T.A. Hsu, H.-P. Hsieh, S.- E. Chuang, G.-M. Lai, Cancer Lett. 246, 237 (2007) http://dx.doi.org/10.1016/j.canlet.2006.03.004[Crossref]
  • [7] B. Domon, C. Costello, Glycoconjugate J. 5, 397 (2005) http://dx.doi.org/10.1007/BF01049915[Crossref]
  • [8] Y. F. Li, H.B. Qu, Y.Y. Cheng, J.Pharm. Biomed. Anal. 47, 407 (2008) http://dx.doi.org/10.1016/j.jpba.2007.12.037[Crossref]
  • [9] Z. Y. Zhu, H. Zhang, L. Zhao, X. Dong, X. Li, Y.F. Chai, G.Q. Zhang, Rapid Commun. Mass Spectrom. 21, 1855 (2007) http://dx.doi.org/10.1002/rcm.3023[Crossref]
  • [10] M. Kivilompolo, V. Obùrka, T. Hyötyläinen, Anal. Bioanal. Chem. 388, 881 (2007) http://dx.doi.org/10.1007/s00216-007-1298-8[Crossref]
  • [11] Y. Zhang, G. Xu, R. Jin, L. Xu, Y. Li, J. China Pharm. Univ. 24, 248 (1993)
  • [12] J. Xia, S. Ji, China Pharm. J. 40, 1895 (2005)
  • [13] Y. Huo, H. Shi, W. Li, M. Wang, X. Li, J. Pharm. Biomed. Anal. 51, 942 (2010) http://dx.doi.org/10.1016/j.jpba.2009.09.032[Crossref]
  • [14] F. Bohlmann, P.K. Mahanta, J. Jakupovic, R.C. Rastogi, A.A. Natu, Phytochemistry 17, 1165 (1978) http://dx.doi.org/10.1016/S0031-9422(00)94308-5[Crossref]
  • [15] A. Stojakowska, K. Michalska, J. Malarz, Phytochem. Anal. 17, 157 (2006) http://dx.doi.org/10.1002/pca.900[Crossref]
  • [16] Y. M. Zhao, M.L. Zhang, Q.W. Shi, H. Kiyota, Chem. Biodivers. 3, 371 (2006) http://dx.doi.org/10.1002/cbdv.200690041[Crossref]
  • [17] W. Blaschek, R. Hänsel, K. Keller, J. Reichling, H. Rimpler, G. Schneider, Hagers Handbuch der Pharmazeutischen Praxis, Vol. 2: Drogen A-K (Springer, Heidelberg, 1998) http://dx.doi.org/10.1007/978-3-642-58928-7[Crossref]
  • [18] I. Spiridon, R. Bodîrlău, C.A. Teacă, Cent. Eur. J. Biol. 6(3), 388 (2011) http://dx.doi.org/10.2478/s11535-011-0028-6[Crossref]
  • [19] R. J. Robbins, J. Agric. Food Chem. 51, 2866 (2003) http://dx.doi.org/10.1021/jf026182t[Crossref]
  • [20] T. Katsube, H. Tabata, Y. Ohta, Y. Yamasaki, E. Anuurad, K. Shiwaku, Y. Yamane, J. Agric. Food Chem. 52, 2391 (2004) http://dx.doi.org/10.1021/jf035372g[Crossref]
  • [21] W. Li, Y. Gao, J. Zhao, Q. Wang, J. Agric. Food Chem. 55, 8478 (2007) http://dx.doi.org/10.1021/jf071696j[Crossref]
  • [22] K. Mruthunjaya, V. I. Hukkeri, Pharmacognosy Magazine 4(23), 42 (2008)
  • [23] R. Govindarajan, S. Rastogi, M. Vijayakumar, A. Shirwaikar, A.K.S. Rawat, S. Mehrotra, P. Pushpangadan, Biol. Pharm. Bull. 26, 1424 (2003) http://dx.doi.org/10.1248/bpb.26.1424[Crossref]
  • [24] K. N. Muko, F.C. Ohiri, Fitoterapia 71, 65 (2000) http://dx.doi.org/10.1016/S0367-326X(99)00123-9[Crossref]
  • [25] M. Pinelo, M. Rubilar, M. Jerez, J. Sineiro, M.J. Núñez, J. Agric. Food Chem. 53, 2111 (2005) http://dx.doi.org/10.1021/jf0488110[Crossref]
  • [26] I. Spiridon, S. Colceru, N. Anghel, C.A. Teacă, R. Bodîrlău, A. Armatu, Nat. Prod. Res. 25(27), 1657 (2011) http://dx.doi.org/10.1080/14786419.2010.521502[Crossref]
  • [27] R. M. Alonso-Salces, K. Ndjoko, E.F. Queiroz, J.R. Ioset, K. Hostettmann, L.A. Berrueta, B. Gallo, F. Vicente, J. Chromatogr. A 1046, 89 (2004)
  • [28] H. S. Lee, B.W. Widmer, In: L.M.L. Nollet (Ed.), Handbook of Food Analysis (Marcel Dekker, New York, 1996) 821
  • [29] D. Huang, B. Ou, R.L. Prior, J. Agric. Food Chem. 53, 1841 (2005) http://dx.doi.org/10.1021/jf030723c[Crossref]
  • [30] R. L. Prior, X. Wu, K. Schaich, J. Agric. Food Chem. 53, 4290 (2005) http://dx.doi.org/10.1021/jf0502698[Crossref]
  • [31] A. Wojdyło, J. Oszmianski, R. Czemerys, Food Chem. 105, 940 (2007) http://dx.doi.org/10.1016/j.foodchem.2007.04.038[Crossref]
  • [32] A. Stojakowska, B. Kedzia, W. Kisiel, Fitoterapia 76, 687 (2005) http://dx.doi.org/10.1016/j.fitote.2005.05.003[Crossref]
  • [33] R. Jaiswal, J. Kiprotich, N. Kuhnert, Phytochemistry 72, 781 (2011) http://dx.doi.org/10.1016/j.phytochem.2011.02.027[Crossref]
  • [34] H. J. You, S.B. Seo, C.S. Seo, Antibacterial and anti-inflammatory compositions with Inula helenium L. extract and water soluble chitosan, US patent 6521268 (2003)
  • [35] C. A. Rice-Evans, N.J. Miller, G. Paganga, Free Rad. Biol. Med. 20, 933 (1996) http://dx.doi.org/10.1016/0891-5849(95)02227-9[Crossref]
  • [36] J. W. Han, B. G. Lee, Y. K. Kim, J.W. Yoon, H. K. Jin, S. Hong, H. Y. Lee, K. R. Lee, H.W. Lee, Br. J. Pharmacol. 133, 503 (2001) http://dx.doi.org/10.1038/sj.bjp.0704099[Crossref]
  • [37] E. Middleton Jr., C. Kandaswami, T.C. Theoharides, Pharmacol. Rev. 52, 673 (2000)
  • [38] P. G. Pietta, J. Nat. Prod. 63, 1035 (2000) http://dx.doi.org/10.1021/np9904509[Crossref]
  • [39] M. Kassim, M. Achoui, M. Mansor, K.M. Yusoff, Fitoterapia 81, 1196 (2010) http://dx.doi.org/10.1016/j.fitote.2010.07.024[Crossref]
  • [40] C. Rice-Evans, Curr. Med. Chem. 8(7), 797 (2001) http://dx.doi.org/10.2174/0929867013373011[Crossref]
  • [41] J. S. Flora, Oxid. Med. Cell. Longev. 2(4), 191 (2009) http://dx.doi.org/10.4161/oxim.2.4.9112[Crossref]
  • [42] M. Di Rosa, D.A. Willoughby, J. Pharm. Pharmacol. 23(4), 297 (1971) http://dx.doi.org/10.1111/j.2042-7158.1971.tb08661.x[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11532-013-0295-3
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.