In vitro surface biocompatibility of high-content silicon-substituted calcium phosphate ceramics

• Autorzy: Nasser Mostafa , Abdallah Shaltout , Lachezar Radev , Hassan Hassan
• Języki publikacji: EN

Abstrakty

EN

The present work investigates surface biocompatibility of silicon-substituted calcium phosphate ceramics. Different silicon-substituted calcium phosphate ceramic bodies were prepared from co-precipitated powders by sintering at 1300°C. The in vitro bioactivity of the ceramics was assessed in simulated body fluid (SBF) at 37°C for periods up to 4 weeks. The changes in the surface morphology and composition were determined by scanning electron microscopy (SEM) coupled with electron probe microanalysis and energy dispersive spectrometer (EDX). Inductively coupled plasma optical emission spectroscopy (ICP-OES) was used to observe the change in ionic concentration of SBF after removal of the samples. The bioactivity of the ceramics increased with an increasing silicate ion substitution in a systematic way. The surface of ceramics with 2.23% silicon substitution was partially covered with apatite layer after one week, while ceramics with 8.1% silicon substitution were completely covered with apatite in the first week. The porous microstructure of high-concentration Si-substituted ceramics helps the dissolution of surface ions and the leaching process. This allows SBF to reach supersaturation in a short time and accelerate the deposition of apatite layer. [...]

Słowa kluczowe

EN

Hydroxyapatite; Biocompatibility; SBF; Silicon substitution; Silicocarnotite

• Czasopismo: Open Chemistry
• Rocznik: 2013
• Tom: 11
• Numer: 2
• Strony: 140-150

Daty

wydano

2013-02-01

online

2012-11-29

Twórcy

autor

Nasser Mostafa,

autor

Abdallah Shaltout

autor

Lachezar Radev

• Department of Fundamental Chemical Technology, University of Chemical Technology and Metallurgy, 1756, Sofia, Bulgaria

autor

Hassan Hassan

• Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt

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Identyfikatory

DOI

10.2478/s11532-012-0142-y