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2010 | 8 | 5 | 1078-1085
Tytuł artykułu

Conductometric studies on the stability of copper complexes with different oligosaccharides

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Bioactive copper complexes with pullulan or dextran oligosaccharides are the subject of intensive research mainly because of their possible application in veterinary and human medicine. The thermal stability and stability under oxidative conditions of the Cu(II) complexes with reduced low-molar pullulan or dextran were investigated in this paper, using a conductometric method. The influence of ligand constitutions on the stability of the complexes was examined on the basis of ligand property. Forced degradation studies were performed on bulk sample of complexes by using heat (25, 40 and 60°C) and an oxidation agent (0.1, 0.5, 1.0 and 10.0% v/v hydrogen peroxide). It can be concluded, according to the results obtained (by examining conductivity during the forced degradation studies), that Cu(II) complexes show a large pharmaceutical stability for both tests. [...]
Słowa kluczowe
Wydawca

Czasopismo
Rocznik
Tom
8
Numer
5
Strony
1078-1085
Opis fizyczny
Daty
wydano
2010-10-01
online
2010-09-05
Twórcy
autor
  • Department of Pharmaceutics, Faculty of Technology, University of Nis, Leskovac, 16000, Serbia, ici_teh@yahoo.com
  • Department of Pharmaceutics, Faculty of Technology, University of Nis, Leskovac, 16000, Serbia
autor
  • Department of Pharmaceutics, Faculty of Technology, University of Nis, Leskovac, 16000, Serbia
  • Department of Pharmaceutics, Faculty of Technology, University of Nis, Leskovac, 16000, Serbia
Bibliografia
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  • [13] G. Nikolić, M. Cakić, Ž. Mitić, R. Nikolić, Lj. Ilić, Chem. Ind. 59(1–2), 9 (2005)
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  • [15] M. Cakić, Ž. Mitić, G.S. Nikolić, Lj. Ilić, G.M. Nikolić, Spectroscopy 22(2–3), 177 (2008)
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  • [23] Ž. Mitić, G.S. Nikolić, M. Cakić, P. Premović, Lj. Ilić, EUCMOS-2008 XXIX European Congress on Molecular Spectroscopy, 01–05 Sep. 2008, Opatija, Croatia (Conference Proceedings, 2008) 197
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11532-010-0082-3
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