PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Czasopismo
2010 | 8 | 3 | 543-549
Tytuł artykułu

Synthesis and characterization of new copper(II) complex compounds with chlorhexidine. Part I

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Three new copper(II) complex compounds with chlorhexidine diacetate as a ligand have been prepared and characterized by elemental and thermogravimetrical analyses, molar conductances, magnetic susceptibility measurements, infrared, electronic and EPR spectra. The complexes correspond to the formulas: [Cu2(CHX)Cl4]·2C2H5OH, [Cu2(CHX)Br4]·2C2H5OH and [Cu2(CHX)(CH3COO)2] (CH3COO)2·2C2H5OH, where CHX = chlorhexidine, their composition and stereochemistry depending on the reaction conditions and the metal salt used. Chlorhexidine acts as neutral tetradentate NNNN donor, coordinating through the four imine nitrogen atoms. Investigations on antimicrobial activity in vitro show that all the complexes are active against the tested microorganisms, the complex with chloride being more active against Gram negative bacteria than chlorhexidine diacetate.. [...]
Słowa kluczowe
Wydawca

Czasopismo
Rocznik
Tom
8
Numer
3
Strony
543-549
Opis fizyczny
Daty
wydano
2010-06-01
online
2010-04-25
Twórcy
  • Faculty of Pharmacy, Ovidius University, Constanţa, 900470, Romania
  • Research Development National Institute for Physics and Nuclear, Engineering Horia Hulubei, Bucharest-Măgurele, 077125, Romania
  • Faculty of Chemistry, University of Bucharest, Bucharest, 020462, Romania
Bibliografia
  • [1] P. Ray, Chem. Rev. 61, 313 (1961) http://dx.doi.org/10.1021/cr60212a001[Crossref]
  • [2] J.C.Y. Woo, V.G. Yuen, K.H. Thompson, J.H. McNeill, C. Orvig, J. Inorg. Biochem. 76, 251 (1999) http://dx.doi.org/10.1016/S0162-0134(99)00152-X[Crossref]
  • [3] D. Sweeney, M.L. Raymer, T.D. Lockwood, Biochem. Pharmacol. 66, 663 (2003) http://dx.doi.org/10.1016/S0006-2952(03)00338-1[Crossref]
  • [4] L. Patron, M. Giurginca, G.M. Pătrînoiu, N. Iftimie, A. Meghea, Rev. Roum. Chim. 50, 457 (2005)
  • [5] G. McDonnell, A.D. Russell, Clin. Microbiol. Rev. 12, 147 (1999)
  • [6] M.C. Kudiyirickal, R. Ivančaková, Acta Med. 51, 3 (2008)
  • [7] M.J. Jeansonne, R.R. White, J. Endod. 20, 276 (1994) http://dx.doi.org/10.1016/S0099-2399(06)80815-0[Crossref]
  • [8] D.G. Bates, J.M. Navia, Arch. Oral Biol. 24, 799 (1979) http://dx.doi.org/10.1016/0003-9969(79)90041-4[Crossref]
  • [9] K. Skjoerland, P. Gjermo, G. Rolla, Scand. J. Dent. Res. 86, 103 (1978)
  • [10] A. Waerhaug, P. Gjermo, G. Rolla, J. Johanssen, J. Clin. Periodont. 11, 176 (1984) http://dx.doi.org/10.1111/j.1600-051X.1984.tb01321.x[Crossref]
  • [11] J.E. Moermann, H.R. Muehlemann, J. Dent. Res. 2, 135 (1983) [Crossref]
  • [12] S.M. Waler, G. Rolla, Acta Odontol. Scand. 38, 213 (1980) http://dx.doi.org/10.3109/00016358009003491[Crossref]
  • [13] C.Gh. Macarovici, Quantitative Inorganic Chemical Analysis (Ed. Acad. RSR, Bucharest, 1979)
  • [14] S. Singh, R. Malhotra, K.S. Dhindsa, Proc. Nat. Acad. Sci. India 68(A), 217 (1998)
  • [15] P.V. Babykutty et al., J. Inorg. Nucl. Chem. 36, 3685 (1974) http://dx.doi.org/10.1016/0022-1902(74)80148-X[Crossref]
  • [16] R.H. Skabo, P.W. Smith, Aust. J. Chem. 22, 659 (1969)
  • [17] P.V. Bharatam, D.S. Patel, P. Iqbal, J. Med. Chem. 48, 7615 (2005) http://dx.doi.org/10.1021/jm050602z[Crossref]
  • [18] K. Nakamoto, Infrared Spectra of Inorganic and Coordination Compounds (Wiley and Sons, New York, 1986)
  • [19] M. Zhu, L. Lu, P. Yang, X. Jin, Acta Cryst. E 58, 217 (2002) http://dx.doi.org/10.1107/S1600536802007092[Crossref]
  • [20] M. Zhu, L. Lu, P. Yang, X. Jin, Acta Cryst. E 58, 272 (2002) http://dx.doi.org/10.1107/S1600536802007869[Crossref]
  • [21] R. Olar, M. Badea, M.N. Grecu, D. Marinescu, V. Lazar, C. Balotescu, J. Therm. Anal. Calor. 92, 239 (2008) http://dx.doi.org/10.1007/s10973-007-8767-3[Crossref]
  • [22] R. Olar, M. Badea, E. Cristurean, C. Pârnău, D. Marinescu, J. Therm. Anal. Calor. 84, 53 (2006) http://dx.doi.org/10.1007/s10973-005-7177-7[Crossref]
  • [23] D.K. Dwivedi, B.V. Agarwala, A.K. Dey, J. Indian Chem. Soc. 65, 461 (1988)
  • [24] D. Sen, J. Chem. Soc. A, 2900 (1969) [Crossref]
  • [25] A.B.P. Lever, Inorganic Electronic Spectroscopy, 2nd edition (Elsevier, Amsterdam-Oxford-New York-Tokyo, 1984)
  • [26] D. Kivelson, R. Nieman, J. Chem. Phys. 35, 149 (1961) http://dx.doi.org/10.1063/1.1731880[Crossref]
  • [27] P. Bindu, M.R.P. Kurup, T.R. Satyakeerthy, Polyhedron 18, 321 (1999) http://dx.doi.org/10.1016/S0277-5387(98)00166-1[Crossref]
  • [28] M.F. Hassan, R. Das, A. Khan, M.S. Hossain, M. Rahman, Advan. Biol. Res. 3, 53 (2009)
  • [29] R.R. Thanigaiarassu, K. Kannabiran, V.G. Khanna, J. Pharm. Res. 2, 273 (2009)
  • [30] S. Sasidharan, I. Darah, M.J. Noordin, Indian J. Pharmacol. 40, 227 (2008) http://dx.doi.org/10.4103/0253-7613.44155[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11532-010-0028-9
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.