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2010 | 8 | 3 | 639-645
Tytuł artykułu

Synthesis, characterization and antitumor activity of Cu(II), Co(II), Zn(II) and Mn(II) complex compounds with aminothiazole acetate derivative

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
This paper presents the synthesis of complex compounds of type [M(L1)2], where M(II)= Cu (1), Co (2), Zn (3), L1=2-aminothiazole-4-acetate and [Mn(L1)2(H2O)] (4) using ethyl 2-(2-aminothiazole-4-yl) acetate (L), and characterization by elemental analysis, magnetic susceptibilities, IR, 1H-NMR, UV-Vis spectroscopy and for [Mn(L1)2(H2O)] also by X-ray diffraction. In vitro cytotoxicity studies were performed on human cervix adenocarcinoma, HeLa cells. The antitumor selectivity was assessed using normal human peripheral blood mononuclear cells, PBMC as control. [...]
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Wydawca

Czasopismo
Rocznik
Tom
8
Numer
3
Strony
639-645
Opis fizyczny
Daty
wydano
2010-06-01
online
2010-04-25
Twórcy
  • Department of Biochemistry, University of Belgrade, Faculty of Chemistry, 11000, Belgrade, Serbia
autor
  • Inorganic Chemistry Department, University “Politehnica” of Bucharest, 011061, Bucharest, Romania
  • Faculty of Chemistry, Department of Inorganic Chemistry, University of Belgrade, 11000, Belgrade, Serbia
  • C.D. Nenitescu Center of Organic Chemistry of the Romanian Academy, 71141, Bucharest, Romania
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11532-010-0022-2
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