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2010 | 8 | 3 | 536-542
Tytuł artykułu

Surfactant to dye binding degree method for the determination of fluvoxamine maleate and citalopram hydrobromide in pharmaceuticals

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The surfactant to dye binding degree (SBDB) methodology was used to determine fluvoxamine maleate and citalopram hydrobromide. Neutral red and sodium dodecyl sulfate (SDS) were used as the dye and surfactant, respectively, to form dye-surfactant aggregates. When a cationic drug is added to dye-surfactant mixture, it interacts with the surfactant and decreases the dye-surfactant binding degree. This decrease is proportional to the drug concentration. This was measured by monitoring the absorbance changes of the dye at 532 nm. Under the optimum conditions, the calibration graphs were linear over the range of 1.2–15 μg mL−1 and 1.1–15 μg mL−1 for fluvoxamine maleate and citalopram hydrobromide, respectively. The detection limits (signal to noise ratio = 3) were found to be 0.37 and 0.35 μg mL−1, for fluvoxamine maleate and citalopram hydrobromide, respectively. [...]
Wydawca

Czasopismo
Rocznik
Tom
8
Numer
3
Strony
536-542
Opis fizyczny
Daty
wydano
2010-06-01
online
2010-04-25
Twórcy
  • Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran, amjadi@tabrizu.ac.ir
  • Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran
  • Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11532-010-0011-5
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