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2014 | 16 | 3 | 97-105
Tytuł artykułu

The Formation of Polycomplexes of Poly(Methyl Vinyl Ether-Co-Maleic Anhydride) and Bovine Serum Albumin in the Presence of Copper Ions

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Języki publikacji
The binary and ternary complex formations of poly(methyl vinyl ether-co-maleic anhydride) (PMVEMA) with copper ions and with bovine serum albumin (BSA) in the presence of copper ions in phosphate buffer solution at pH = 7 were examined by the techniques of UV-visible, fluorescence, dynamic light scattering, atomic force microscopy measurements. In the formation of binary complexes of PMVEMA-Cu(II), the addition of copper ions to the solution of PMVEMA in phosphate buffer solution at pH = 7 forms homogeneous solutions when the molar ratio of Cu(II)/MVEMA is 0.5. Then the formations of ternary complexes of PMVEMA-Cu(II)-BSA were examined. Study analysis revealed that the toxicities of polymer-metal and polymer-metal-protein mixture solutions depend on the nature and ratio of components in mixtures.

Opis fizyczny
  • Üsküdar University, Faculty of Engineering and Natural Sciences, Department of Bioengineering, 34662 Uskudar-Istanbul, Turkey,
  • Yildiz Technical University, Faculty of Chemical and Metallurgical Engineering, Department of Bioengineering, 34220 Esenler-Istanbul Turkey
  • Istanbul University, Faculty of Engineering, Department of Chemistry, 34320 Avcılar-Istanbul Turkey
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