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2013 | 39 | 1 | 137-145
Tytuł artykułu

CKM Gene G (Ncoi-) Allele Has a Positive Effect on Maximal Oxygen Uptake in Caucasian Women Practicing Sports Requiring Aerobic and Anaerobic Exercise Metabolism

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The search for genes with a positive influence on physical fitness is a difficult process. Physical fitness is a trait determined by multiple genes, and its genetic basis is then modified by numerous environmental factors. The present study examines the effects of the polymorphism of creatine kinase (CKM) gene on VO2max - a physiological index of aerobic capacity of high heritability. The study sample consisted of 154 men and 85 women, who were students of the University School of Physical Education in Poznań and athletes practicing various sports, including members of the Polish national team. The study revealed a positive effect of a rare G (NcoI-) allele of the CKM gene on maximal oxygen uptake in Caucasian women practicing sports requiring aerobic and anaerobic exercise metabolism. Also a tendency was noted in individuals with NcoI-/- (GG) and NcoI-/+ (GA) genotypes to reach higher VO2max levels.
Wydawca

Rocznik
Tom
39
Numer
1
Strony
137-145
Opis fizyczny
Daty
wydano
2013-12-01
online
2013-12-31
Twórcy
autor
  • Department of Physiology, The Eugeniusz Piasecki University School of Physical Education, Poland., gronek@awf.poznan.pl
  • Department of Physiology, The Eugeniusz Piasecki University School of Physical Education, Poland.
  • Department of Physiology, The Eugeniusz Piasecki University School of Physical Education, Poland.
  • Computer Laboratory of the Faculty of Animal Breeding and Biology, Poznań University of Life Sciences, Poland.
Bibliografia
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  • Bouchard C, Rankinen T, Chagnon YC, Rice T, Perusse L, Gagnon J, Borecki I, An P, Leon AS, Skinner JS, Wilmore JH, Province M, Rao DC. Genomic scan for maximal oxygen uptake and its response to training in the HERITAGE Family Study. J Appl Physiol, 2000; 88: 551-559[PubMed]
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  • Nigro JM, Schweinfest CW, Rajkovic A, Pavlovic J, Jamal S, Dottin RP, Hart JT, Kamarck ME, Rae PMM, Carty MD, Martin-DeLeon P. cDNA cloning and mapping of the human creatine kinase M gene to 19q13. Am J Hum Genet, 1987; 40: 115-125
  • Rivera MA, Dionne FT, Wolfarth B, Chagnon M, Simoneau JA, Perusse L, Boulay MR, Gagnon J, Song TMK, Keul J, Bouchard C. Muscle-specific creatine kinase gene polymorphism in elite endurance athletes and sedentary controls. Med Sci Sports Exerc, 1997; 29(11): 1444-1447[Crossref][PubMed]
  • Rivera MA, Perusse L, Simoneau JA, Gagnon J, Dionne FT, Leon AS, Skinner JS, Wilmore JH, Province M, Rao DC, Bouchard C. Linkage between a muscle-specific CK gene marker and VO2max in the HERITAGE Family Study. Med Sci Sports Exerc, 1999; 5: 698-701[Crossref]
  • Sawczuk M, Maciejewska-Karłowska A, Cięszczyk P. A single nucleotide polymorphism rs553668 in ADRA2A gene and Polish elite endurance athlete status. Trends Sport Sci, 2013; 1(2): 30-35
  • Wallimann T, Wyss M, Brdiczka D, Nicolay K, Eppenberger HM. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem J, 1992; 281: 21-40
  • Zhou DQ, Hu Y, Liu G, Gong L, Xi Y, Wen L. Muscle-specific creatine kinase gene polymorphism and running economy responses to an 18-week 5000-m training programme. Br J Sports Med, 2006; 40(12): 988-991
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_hukin-2013-0076
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