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2015 | 87 | 7 | 357-361
Tytuł artykułu

Evaluation Of Antioxidant Defense In Patients With Colorectal Carcinoma

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Cancers are among the most feared diseases of modern civilization. In Poland, colorectal cancer is one of the tumors with the worst prognosis. The ability to cure is primarily dependent on the stage of the disease at the time of diagnosis. The aim of the study was evaluate antioxidant response in patients with colorectal carcinoma. Material and methods. Twenty patients (14 men and 6 women) aged 61.9± 11.1 years with colorectal cancer were included in the study. Twenty healthy subjects (4 men and 16 women) aged 64 ± 15.3 years formed the control group. The erythrocyte activities of antioxidant enzymes, superoxide dismutase (SOD), and glutathione peroxidase (GPx), Results. A significant increase of GPx, and SOD (p < 0.05) were seen in patients compared to healthy controls. Conclusion. The results indicate that the tested antioxidant enzyme activity of glutathione peroxidase and superoxide dismutase is increased in patients diagnosed with colorectal cancer compared to the control group.
Słowa kluczowe
EN
GPx   SOD   colon cancer  
Wydawca
Rocznik
Tom
87
Numer
7
Strony
357-361
Opis fizyczny
Daty
wydano
2015-07-01
otrzymano
2015-07-07
online
2015-09-07
Twórcy
autor
  • Department of General and Colorectal Surgery, Medical University in ŁódźKierownik: prof. dr hab.
  • Department of General and Colorectal Surgery, Medical University in ŁódźKierownik: prof. dr hab.
autor
  • Department of General and Colorectal Surgery, Medical University in ŁódźKierownik: prof. dr hab.
  • Department of Clinical Chemistry and Biochemistry, Medical University in ŁódźKierownik: prof. dr hab.
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_1515_pjs-2015-0069
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