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Tytuł artykułu

Imaging of myocardial infarction with thermoacoustic tomography: An ex vivo study

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
In the present study, we evaluated the feasibility of thermoacoustic tomography (TAT) for imaging of ex vivo mouse hearts with myocardial infarction. A circular scanning TAT system with an unfocused transducer was used to recover the dielectric property distribution of normal andmyocardial infarcted mouse heart tissues. The applicability of this myocardial infarction imaging system was validated using a model of myocardial infarction in two Sprague-Dawley rats and verified through comparison with magnetic resonance imaging (MRI). TAT results not only indicated the location and ischemia and the extent of myocardial ischemia (MI), but also showed good imaging contrast between infarcted and normal myocardium without the use of contrast agent. The experimental results suggest that TAT may provide a unique opportunity to enable real-time precision imaging to determine the site of injury intraoperatively
Słowa kluczowe
Wydawca
Rocznik
Tom
1
Numer
1
Opis fizyczny
Daty
otrzymano
2014-12-01
zaakceptowano
2015-05-18
online
2015-08-18
Twórcy
autor
  • School of Physical Electronics,
    University of Electronic Science and Technology of China,
    Chengdu, 610054, China
autor
  • Department
    of radiology, Beijing Jishuitan hospital, Beijing, 100035, China
autor
  • The Fourth Affiliated Hospital of China Medical University,
    Shenyang, 110032, China
autor
  • School of Physical Electronics,
    University of Electronic Science and Technology of China,
    Chengdu, 610054, China
autor
  • School of Physical Electronics,
    University of Electronic Science and Technology of China,
    Chengdu, 610054, China
Bibliografia
  • [1] Lou, C., & Xing, D. (2010). Temperature monitoring utilisingthermoacoustic signals during pulsed microwave thermotherapy:a feasibility study. International Journal of Hyperthermia,26(4), 338-346.[Crossref][WoS]
  • [2] Nie, L., Xing, D., Zhou, Q., Yang, D., & Guo, H. (2008).Microwave-induced thermoacoustic scanning CT for highcontrastand noninvasive breast cancer imaging. Medicalphysics, 35(9), 4026-4032.[WoS][Crossref]
  • [3] Zhu, L., Xu, L. X., & Chencinski, N. (1998). Quantification ofthe 3-D electromagnetic power absorption rate in tissue duringtransurethral prostatic microwave thermotherapy usingheat transfer model. Biomedical Engineering, IEEE Transactionson, 45(9), 1163-1172.
  • [4] Pham, T., Beigie, C., Park, Y., & Wong, J. Y. (2014). Microbubblesas Theranostics Agents. In Nano-Oncologicals (pp. 329-350).Springer International Publishing.
  • [5] Ogunlade, O., & Beard, P. (2014, March). Electric and magneticproperties of contrast agents for thermoacoustic imaging. InSPIE BiOS (pp. 89432V-89432V). International Society for Opticsand Photonics.
  • [6] Osepchuk, J. M., & Petersen, R. C. (2001). Safety standards forexposure to RF electromagnetic fields. Microwave Magazine,IEEE, 2(2), 57-69.
  • [7] Huang, L., Yao, L., Liu, L., Rong, J., & Jiang, H. (2012). Quantitativethermoacoustic tomography: Recovery of conductivitymaps of heterogeneous media. Applied Physics Letters,101(24), 244106.[WoS][Crossref]
  • [8] Huang, L., Liu, L., Lu, K., Zhong, X., Li, T., Chen, B., & Jiang, H. 3GHz Thermoacoustic Tomography System.
  • [9] Nikolova, N. K. Microwave Biomedical Imaging. Wiley Encyclopediaof Electrical and Electronics Engineering.
  • [10] Janse, M. J., & Wit, A. L. (1989). Electrophysiological mechanismsof ventricular arrhythmias resulting from myocardial ischemiaand infarction. Physiol Rev, 69(4), 1049-1169.
  • [11] Serguei Y. S., Alexander E. B., Vitaly G. P., Yuri E. S., Thomas C.W., Alexander E. S. (2003). Microwave Tomography for Detection/Imaging ofMyocardial Infarction. I. Excised Canine Hearts.Annals of Biomedical Engineering, 31(3), 262-270.[Crossref]
  • [12] Rajiah P., Desai M. Y., Kwon D., Flamm S. D. (2013). MR imagingof myocardial infarction. Sep-Oct, 33(5), 1383-412.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_1515_phto-2015-0003
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