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2014 | 10 | 1 |
Tytuł artykułu

An unusual evolution of a case of Klippel-Trenaunay syndrome

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Klippel-Trenaunay syndrome (KTS) is a rare congenital disorder. KTS can be diagnosed on the basis of any 2 of 3 features: cutaneous capillary malformations, soft tissue or bony hypertrophy and varicose veins. We present an unusual case of KTS complicated by an infection of venous ulcers of the lower limb by larvae. The treatment of infection was a complete debridement; however baseline treatment of KTS is still in evaluation.
Słowa kluczowe
Wydawca

Czasopismo
Rocznik
Tom
10
Numer
1
Opis fizyczny
Daty
wydano
2015-01-01
otrzymano
2015-10-27
zaakceptowano
2015-11-02
online
2015-12-17
Twórcy
  • Department of Oncology, University of Turin, Section of General Surgery, San Luigi Gonzaga Teaching Hospital, Regione Gonzole 10, 10043 Orbassano – Turin (Italy), valtermartino.md@gmail.com
  • University of Turin, Department of Oncology, School of Medicine, Teaching Hospital “San Luigi Gonzaga”, Section of General Surgery, Orbassano, Turin
  • University of Turin, Department of Oncology, School of Medicine, Teaching Hospital “San Luigi Gonzaga”, Section of General Surgery, Orbassano, Turin
  • University of Turin, Department of Oncology, School of Medicine, Teaching Hospital “San Luigi Gonzaga”, Section of General Surgery, Orbassano, Turin
  • University of Turin, Department of Oncology, School of Medicine, Teaching Hospital “San Luigi Gonzaga”, Section of General Surgery, Orbassano, Turin
  • University of Turin, Department of Oncology, School of Medicine, Teaching Hospital “San Luigi Gonzaga”, Section of General Surgery, Orbassano, Turin
autor
  • University of Turin, Department of Oncology, School of Medicine, Teaching Hospital “San Luigi Gonzaga”, Section of General Surgery, Orbassano, Turin
autor
  • University of Turin, Department of Oncology, School of Medicine, Teaching Hospital “San Luigi Gonzaga”, Section of General Surgery, Orbassano, Turin
  • University of Turin, Department of Oncology, School of Medicine, Teaching Hospital “San Luigi Gonzaga”, Section of General Surgery, Orbassano, Turin
Bibliografia
  • [1] Kihiczak GG, Meine JG, Schwartz RA, Janniger CK. Klippel- Trenaunay syndrome: A multisystem disorder possibly resulting from a pathogenic gene for vascular and tissue overgrowth. Int J Dermat 2006;45:883-90.[Crossref]
  • [2] Lorda-Sanchez I, Prieto L, Rodriguez-Pinilla E, Martinez- Frias ML. Increased parental age and number of pregnancies in Klippel-Trenaunay-Weber syndrome. Ann Hum Genet 1998;62:235-39.[Crossref]
  • [3] Klippel M, Trenaunay P. Du naevus variqueux osteohypertrophique. Arch General Med 1900;185:641-72.
  • [4] You CK, Rees J, Gillis DA, Steeves J. Klippel-Trenaunay syndrome: a review. Can J Surg 1983;26:399-403.
  • [5] Wang Q, Timur AA, Szafranski P, Sadgephour A, Jurecic V, Cowell J, et al. Identification and molecular characterization of de novo translocation t(8;14)(q22.3;q13) associated with a vascular and tissue overgrowth syndrome. Cytogenet Cell Genet 2001;95:183-8.
  • [6] Craven N, Wright AL. Familial Klippel-Trenaunay syndrome: a case report. Clin Exp Dermatol 1995;20:76-9.[Crossref]
  • [7] Dubois J, Garel L, Grignon A, David M, Laberge L, Filiatrault D, et al. Imaging of hemangiomas and vascular malformations in children. Acad Radiol 1998;5:390-400.[Crossref]
  • [8] Lee A, Driscoll D, Gloviczki P, Clay R, Shaughnessy W, Stans A. Evaluation and management of pain in patients with Klippel- Trenaunay syndrome: a review. Pediatrics 2005;115:744-9.
  • [9] Maari C, Frieden IJ. Klippel-Trénaunay syndrome: the importance of “geographic stains” in identifying lymphatic disease and risk of complications. J Am Acad Dermatol 2004;51:391-8.[Crossref]
  • [10] Noel AA, Gloviczki P, Cherry KJ Jr, Rooke TW, Stanson AW, Driscoll DJ. Surgical treatment of venous malformations in Klippel-Trénaunay syndrome. J Vasc Surg 2000;32:840-7.[Crossref]
  • [11] Frasier K1, Giangola G, Rosen R, Ginat DT. Endovascular radiofrequency ablation: a novel treatment of venous insufficiency in Klippel-Trenaunay patients. J Vasc Surg 2008;47:1339-45.[WoS][Crossref]
  • [12] Capraro PA, Fisher J, Hammond DC, Grossman JA. Klippel- Trenaunay syndrome. Plast Reconstr Surg 2002;109:2052-9.[WoS]
  • [13] Delis KT, Gloviczki P, Wennberg PW, Rooke TW, Driscoll DJ. Hemodynamic impairment, venous segmental disease, and clinical severity scoring in limbs with Klippel-Trenaunay syndrome. J Vasc Surg 2007;45:561-7.[WoS][Crossref]
  • [14] Pecoraro RE, Reiber GE, Burgess EM. Pathways to diabetic limb amputation: Basis for prevention. Diabetes Care 1990,13: 513-21.[Crossref]
  • [15] O’Meara S, Al-Kurdi D, Ologun Y, Ovington LG. Antibiotics and antiseptics for venous leg ulcers. Cochrane Database Syst Rev. 2010;20:CD003557.
  • [16] Paré A. The battell of S. Quintin (1557). In: Keynes G, editor. The Apologie and Treatise of Ambroise Paré. Chicago: The University of Chicago Press; 1952:68-70.
  • [17] Mumcuoglu KY. Clinical applications for maggots in wound care. Am J Clin Dermatol 2001;2:219-27.[Crossref]
  • [18] Barnard DR. Skeletal-muscular mechanisms of the larva of Lucilia sericata (Meigen) in relation to feeding habit. Pan-Pac Entomol 1977;53:223-9.
  • [19] Chambers L, Woodrow S, Brown AP, Harris PD, Phillips D, Hall M, et al. Degradation of extracellular matrix components by defined proteinases from the greenbottle larva Lucilia sericata used for the clinical debridement of non-healing wounds. Br J Dermatol 2003;148:14-23.
  • [20] Serra, R. , Buffone, G., Molinari, V., et al. : Low molecular weight heparin improves healing of chronic venous ulcers especially in the elderly. International Wound Journal, 2013, Article in press
  • [21] Persico, G., Amato, B., Aprea, G., et al. : The early effects of intravenous L-propionyl carnitine on ulcerative trophic lesions of the lower limbs in arteriopathic patients: A controlled randomized study. Drugs under Experimental and Clinical Research, 1995, 21: 5, 187-198
  • [22] Amato B., Coretti G., Compagna R., et al: Role of matrix metalloproteinases in non-healing venous ulcers. International Wound Journal, 2013, Article in press
  • [23] Serra R. , Grande R., Buffone G., et al.: Extracellular matrix assessment of infected chronic venous leg ulcers: Role of metalloproteinases and inflammatory cytokines. International Wound Journal, 2014 Article in press
  • [24] De Franciscis S., Gasbarro V., Amato B., Buffone G., Grande R., Serra, R.: Hemodynamic surgery versus conventional surgery in chronic venous disease: A multicenter retrospective study . Acta Phlebologica, 2013, 14: 3, 109-114
  • [25] Serra R. , Gallelli L., Conti A., et al. : The effects of sulodexide on both clinical and molecular parameters in patients with mixed arterial and venous ulcers of lower limbs. Drug Design, Development and Therapy, 2014, 8: 13, 519-527[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_1515_med-2015-0084
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