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2014 | 10 | 1 |
Tytuł artykułu

The role of99mTc-MIBI SPECT-CT in reoperation therapy of persistent hyperparathyroidism patients

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
To compare the role of 99mTc-MIBI SPECT-CT image and US in reoperation of persistent secondary hyperparathyroidism patients. A total of 8 persistent secondary hyperparathyroidism patients underwent parathyroidectomy. The sensitivity and accuracy of US and 99mTc-MIBI images before operation were determined. 9 of 14 surgical resection tissues from 8 persistent secondary hyperparathyroidism patients were confirmed to parathyroid hyperplasia. The results showed that the sensitivities were 77.8% and 100%, respectively, for US and 99mTc-MIBI SPECT-CT images. And the accuracies of US and 99mTc-MIBI dual time planar image and SPECT-CT were 50%, 78.6%, respectively. There was significantly difference between two procedures (P=0.021). The superior and inferior localization of glands were both detected by the ultrasound and scintigraphy. Two ectopic parathyroidism nodules were found by 99mTc- MIBI SPECT-CT imaging, while US provided no consistent findings. There was no significantly difference between two procedures (P=0.3). Although two cases of them were not confirmed by pathology, the iPTH of them (800 and 1429 respectively) were much higher than other four cases (<400) pg/ml. PTX is a safe and effective treatment for the patients with persistent SHPT. 99mTc-MIBI planar and SPECT-CT imaging may provide more helps for clinician’s localization the hyperparathyroidism glands accurately.
Wydawca

Czasopismo
Rocznik
Tom
10
Numer
1
Opis fizyczny
Daty
wydano
2015-01-01
otrzymano
2015-07-11
zaakceptowano
2015-10-15
online
2015-12-17
Twórcy
autor
  • Department of Nuclear Medicine, China-Japan Friendship hospital, Beijing 100029, China, wenhua1711@qq.com
autor
  • Department of Nuclear Medicine, China-Japan Friendship hospital, Beijing 100029, China
autor
  • Department of Nuclear Medicine, China-Japan Friendship hospital, Beijing 100029, China
autor
  • Department of Nuclear Medicine, China-Japan Friendship hospital, Beijing 100029,
Bibliografia
  • [1] Hamouda M., Ben Dhia N., Aloui S., et al., Surgical treatment of secondary hyperparathyroidism in patients with chronic renal failure, Nephrol. Ther., 2011, 7, 105-110[WoS][Crossref]
  • [2] Xiaowei W., Zhiyong C., Huagang Z.H.U., Progress in diagnosis and treatment of persistent and recurrent hyperparathyroidism, Anhui Medical and Pharmaceutical Journal, 2011, 15, 666-668
  • [3] Li Y., Ling Z., Peng L.I.U., et al., Therapeutic evaluation of parathyroidectomy for 89 cases with refractory secondary hyperparathyroid-ism, Chinese Journal of Blood Purification, 2009, 8, 431-436
  • [4] Clark O.H., Duh Q.Y., Kebebew E., Textbook of Endocrine Surgery, Second Edition, Philadelphia, Elsevier Saunders, 2005, 518
  • [5] Kalantar-Zadeh K., Shah A., Duong U., et al., Kidney bone disease and mortality in CKD, revisiting the ro1e of vitamin D, calcimimetics, alkaline phosphatase and minerals, Kidney Int., 2010, 117, S10-2l[WoS]
  • [6] Ling Z., Wenbo W., Li Y., et al., Total parathyroidectomy with forearm autograft in the treatment of a patient with secondary hyperparathyroidism, Chinese Journal of Blood Purification, 2011,10, 277-282
  • [7] Li Y., Zhan H., Ling Z., et al., Is autotransplantation needed for SPHT patients after undergoing the whole excision of parathyroid glands? Chinese Journal of Blood Purification, 2011, 10, 233-235
  • [8] Chungui S., Zhiyong Y., Tianyan Z., The clinical value of ultrasonography in patients with secondary hyperparathyroidism performing maintenance hemodialysis, Chinese Medical Herald, 2011, 8, 87-88
  • [9] Lishi Z., Xiaojian L., Ling Z., et al.. Value of dual-phase 99Tcm-MIBI scintigraphy and SPECT/CT in the localization diagnosis of secondary hyperparathyroidism, Chinese Journal of Blood Purification, 2011, 10, 242-245
  • [10] Wakamatsu H., Noguchi S.,Yamashita H., et al., Technetium-99m- tetrofosmin for parathyroid scintigraphy: a direct comparison with (99m)Tc-MIBI, (201)T1, MRI and US, Eur. J. Nucl. Med., 2001, 28, 1817-1827
  • [11] Ling T., Rongfu W., Li H., et al., Clinical Value of Radionuclide Parathyroid Imaging in Hyperparathyroidism, Chinese Journal of Medical Imaging Technology, 2003, 19, 863-865
  • [12] Binbin Z., Qian W., Yuan L., Parathyroid hormone testing and 99Tcm-MIBI imaging of hyperparathyroidism, Chinese Journal of Nuclear Medicine and Molecular Imaging, 2011, 31, 263-266
  • [13] Haiming L., Yong G.U., Jun X., et al., Clinical effect of total parathyroidectomy with forearm autograft on uremic patients
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_1515_med-2015-0064
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