Ketamine in outpatient arthroscopic shoulder surgery: Effects on postoperative pain, hemodynamic stability and process times

• Autorzy: Hanna Schotola , Karl-Christian Kirsch , Jan Höcker , Michael Egan , Benedikt Büttner , Christoph Wiese , Ashham Mansur , José Maria Hinz , Ingo Bergmann
• Języki publikacji: EN

Abstrakty

EN

Background: Pain after arthroscopic shoulder surgery is often severe, and establishing a pain treatment regimen that does not delay discharge can be challenging. The reported ability of ketamine to prevent opioid-induced hyperalgesia has not been investigated in this particular setting. Methods: 300 adult patients scheduled for shoulder arthroscopy under general anesthesia were recruited for this observational clinical trial and were allotted to either receive 1mg/kg IV bolus of ketamine before surgery (ketamine group, KG) or to a control group (CG) without ketamine. NRS pain scores were obtained on the operative day and on postoperative days 1 and 2 and compared between groups. Secondary variables were blood pressure, heart rate, process times, satisfaction with the anesthetic and unwanted effects. Results: Pain severity did not differ significantly between the groups at any time. Propofol injection rate and cumulative dose were higher in the KG. Heart rates and blood pressures were similar. Time to emergence and time in PACU were longer and vomiting was more frequent in patients given ketamine. Conclusion: Preoperative low-dose ketamine added to a general anesthetic does not reduce perioperative pain after outpatient shoulder arthroscopy. It increases procedural times and the incidence of PONV.

Słowa kluczowe

EN

Ketamine; outpatient; day surgery; postoperativepain; general anaesthesia

• Czasopismo: Open Medicine
• Rocznik: 2014
• Tom: 10
• Numer: 1

Daty

otrzymano

2015-02-26

zaakceptowano

2015-05-18

online

2015-05-28

Twórcy

autor

Hanna Schotola

• Department of Anaesthesiology, Emergency and
  Intensive Care Medicine, University of Göttingen Medical School,
  Göttingen, Germany

autor

Karl-Christian Kirsch

• Department of Anesthesiology
  and Intensive Care Medicine, University Hospital Schleswig-Holstein,
  Campus Kiel, Kiel, Germany

autor

Jan Höcker

• Department of Anesthesiology
  and Intensive Care Medicine, University Hospital Schleswig-Holstein,
  Campus Kiel, Kiel, Germany

autor

Michael Egan

• Department of Anaesthesiology, Emergency and
  Intensive Care Medicine, University of Göttingen Medical School,
  Göttingen, Germany

autor

Benedikt Büttner

• Department of Anaesthesiology, Emergency and
  Intensive Care Medicine, University of Göttingen Medical School,
  Göttingen, Germany

autor

Christoph Wiese

• Clinic for Anesthesiology, University Hospital
  Regensburg, Germany

autor

Ashham Mansur

• Department of Anaesthesiology, Emergency and
  Intensive Care Medicine, University of Göttingen Medical School,
  Göttingen, Germany

autor

José Maria Hinz

• Department of Anaesthesiology, Emergency and
  Intensive Care Medicine, University of Göttingen Medical School,
  Göttingen, Germany

autor

Ingo Bergmann

• Center for Anesthesiology,
  Emergency and Intensive Care Medicine, University Hospital Göttingen,
  Robert-Koch Str. 40, 37075 Göttingen, Germany

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Identyfikatory

DOI

10.1515/med-2015-0043