Cognitive impairment predicts social disability in persons with epilepsy

• Autorzy: Krzysztof A. Bujarski , Gabriella Wozniak , Erik J. Kobylarz
• Języki publikacji: EN

Abstrakty

EN

Introduction. Cognitive dysfunction is one of the main comorbidities of epilepsy which co-exists with seizures and contributes to the adverse impact of the disease on employment, education and interpersonal relationships. A fundamental question regarding cognitive dysfunction in epilepsy goes as follows: in comparison to seizures, what role does cognitive dysfunction play in causing social disability? The purpose of this review was to evaluate our understanding of the role cognitive impairment plays in social disability in persons with epilepsy (PWE). We systematically searched the medical literature and identified studies which assessed the impact of seizures and cognitive function on some aspect of social disability in PWE. Results and Discussion. We identified 12 studies which adequately measured all variables in non-surgical cohorts, and 9 studies of cohorts following epilepsy surgery. We found evidence from non-surgical and from surgical series that cognitive variables strongly correlate with levels of social disability. Conclusions. We conclude that efforts to better understand the origins of cognitive dysfunction in epilepsy and subsequently at developing treatment modalities will be needed in order to reduce the degree of social disability caused by the condition.

Słowa kluczowe

EN

epilepsy; cognitive impairment; social disability

• Czasopismo: Journal of Epileptology
• Rocznik: 2014
• Tom: 22
• Numer: 2
• Strony: 89-97

Daty

wydano

2014-12-01

otrzymano

2014-05-19

zaakceptowano

2014-08-20

online

2015-03-01

Twórcy

autor

Krzysztof A. Bujarski

• Geisel School of Medicine at Dartmouth,

autor

Gabriella Wozniak

• Dartmouth-Hitchcock Medical Center, Geisel School of Medicine at Dartmouth

autor

Erik J. Kobylarz

• Geisel School of Medicine at Dartmouth

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Identyfikatory

DOI

10.1515/joepi-2015-0016