Investigation of the hepatoprotective properties of “Phytovenol” capsules on the model of medicamentous hepatitis in rats

• Autorzy: Oleg Gerush , Olena Lenytska , Larysa Yakovleva , Liudmyla Gladkova , Igor Gerush
• Języki publikacji: EN

Abstrakty

EN

This scientific paper is an investigation of the pharmacological activity of the new medical preparation “Phytovenol” (capsules in the dose of 150 mg/kg) on the pattern of hepatitis in rats induced by paracetamol administration. The authors of the article, for the first time under experimental conditions, detected a hepatoprotective effect that was brought about by “Phytovenol” capsule administration. This is realized due to the antioxidant, antitoxic and anticytolytic activity of the examined medicine. The study found that its efficacy is not lower than the classical hepatoprotector - “Silibor” tablets. The results obtained suggest that it is possible to extend the range of available hepatoprotectors and improve the quality of treatment for liver diseases, by introducing “Phytovenol” capsules into medical practice.

Słowa kluczowe

EN

liver; hepatitis; “Phytovenol” capsules; hepatoprotective action

• Czasopismo: Current Issues in Pharmacy and Medical Sciences
• Rocznik: 2014
• Tom: 27
• Numer: 4
• Strony: 240-242

Daty

wydano

2014-12-01

otrzymano

2014-11-07

zaakceptowano

2014-12-12

online

2015-03-03

Twórcy

autor

Oleg Gerush

• Bukovinian State Medical University, Department of Pharmacy, Department of Bio-organic and Biological Chemistry and Clinical Biochemistry, 2 Teatralna Sq., Chernivtsi, Ukraine,

autor

Olena Lenytska

• National Pharmaceutical University, Department of Pharmacoeconomics, Central Scientific-Research Laboratory, Kharkiv, Ukraine

autor

Larysa Yakovleva

• National Pharmaceutical University, Department of Pharmacoeconomics, Central Scientific-Research Laboratory, Kharkiv, Ukraine

autor

Liudmyla Gladkova

• National Pharmaceutical University, Department of Pharmacoeconomics, Central Scientific-Research Laboratory, Kharkiv, Ukraine

autor

Igor Gerush

• Bukovinian State Medical University, Department of Pharmacy, Department of Bio-organic and Biological Chemistry and Clinical Biochemistry, 2 Teatralna Sq., Chernivtsi, Ukraine

Bibliografia

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Identyfikatory

DOI

10.1515/cipms-2015-0024