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2015 | 13 | 1 |
Tytuł artykułu

Immunoactive ionic liquids based on 2-hydroxyethylamines and 1-R-indol-3-ylsulfanylacetic acids. Crystal and molecular structure of immunodepressant tris-(2-hydroxyethyl)ammonium indol-3-ylsulfanylacetate

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Języki publikacji
EN
Abstrakty
EN
Immunoactive ionic liquids (2-hydroxyethyl)ammonium 1-R-indol-3-ylsulfanyl-acetates HN+R1R2(CH2CH2OH) ∙ -O(O)CCH2S-Ind-R3-1 (1-5), were synthesized by the reaction of (2-hydroxyethyl)amines with indol-3-ylsulfanylacetic- or 1-benzylindol-3-ylsulfanylacetic acid. 1: R1 = R2 = CH2CH2OH, R3 = H; 2: R1 = СН3,R2=CH2CH2OH, R3 = H; 3: R1 = R2 = CH3, R3 = H; 4: R1 = R2 = CH2CH2OH, R3 = СH2С6Н5; 5: R1 = СН3; R2 = CH2CH2OH; R3 = СH2С6Н5. The structure of each compound was elucidated by IR, NMR 1H, 13С, and 15N techniques and their composition was confirmed by elemental analysis. The crystal structure of tris-(2-hydroxyethyl) ammonium indol-3-ylsulfanylacetate was investigated by X-ray diffraction analysis. Immunoactive properties of the title compounds were screened.
EN
Wydawca
Czasopismo
Rocznik
Tom
13
Numer
1
Opis fizyczny
Daty
otrzymano
2014-04-15
zaakceptowano
2014-06-17
online
2014-11-01
Twórcy
  • A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, 664033 Irkutsk, Russia
  • A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, 664033 Irkutsk, Russia
  • A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, 664033 Irkutsk, Russia
  • Research Institute of Clinical Immunology, Siberian Branch of the Russian Academy of Medical Sciences, 630099 Novosibirsk, Russia
autor
  • Institute of Chemistry, University of Potsdam, D-14476 Potsdam, Germany
Bibliografia
  • [1] Hough W.L., Smiglak M., Rodrıґguez H., Swatloski R.P.,Spear S.K., Daly D.T., et al., New J. Chem., 2007, 31, 1429, DOI: 10.1039/B706677P[Crossref]
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  • [14] Sheldrick G.M., SHELXS-97: Program for the Solution of Crystal Structures, University of Göttingen, Germany, 1997
  • [15] Sheldrick G.M., SHELXL-2013, Program for the Refinement of Crystal Structures, University of Göttingen, Germany, 2013
  • [16] Brandenburg K., DIAMOND, Version 3.1, Crystal Impact, Bonn, 2005
  • [17] Levkovskaya G.G., Rudyakova E.V., Mirskova A.N., Russ. J. Org. Chem., 2002, 38, 1478
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_1515_chem-2015-0018
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