Differences in basal DNA damage in blood cells from men and women

• Autorzy: Avdulla J. Alija , Andrew Richard Collins , Shemsedin Dreshaj , Fisnik Asllani , Ismet D. Bajraktari , Nikolaus Bresgen , Peter M. Eckl
• Języki publikacji: EN

Abstrakty

EN

We have recently shown that inhabitants of two polluted areas in Kosovo display more DNA damage (strand breaks in blood cell DNA) than do residents of a cleaner area. Here, we present additional analyses of these data and discuss additional data sets from Kosovo. Based on our data as well as the available data from other authors, age and sex-related differences in DNA damage or in susceptibility to DNA-damaging agents in the environment should be carefully considered when designing biomonitoring studies and when carrying out statistical analysis of the data.

Słowa kluczowe

EN

Comet Assay; DNA damage; Environmentalpollution; Kosovo

• Czasopismo: Biomonitoring
• Rocznik: 2016
• Tom: 3
• Numer: 1

Daty

otrzymano

2016-02-04

zaakceptowano

2016-02-22

online

2016-03-17

Twórcy

autor

Avdulla J. Alija

• Department of Biology, University
  of Prishtina, Xhorxh Bush, n.n.,10000, Prishtina, Kosovo

autor

Andrew Richard Collins

• Department of Nutrition, Institute of Basic
  Medical Sciences, University of Oslo, PB 1046 Blindern, 0316 Oslo,
  Norway.

autor

Shemsedin Dreshaj

• Faculty of Medicine, University of Prishtina,
  Xhorxh Bush Street, n.n.,10000, Prishtina, Kosovo

autor

Fisnik Asllani

• Department of Biology, University
  of Prishtina, Xhorxh Bush, n.n.,10000, Prishtina, Kosovo

autor

Ismet D. Bajraktari

• Department of Biology, University
  of Prishtina, Xhorxh Bush, n.n.,10000, Prishtina, Kosovo

autor

Nikolaus Bresgen

• Department of Cell Biology, University
  of Salzburg, Hellbrunnerstr. 34, A-5020 Salzburg, Austria

autor

Peter M. Eckl

• Department of Cell Biology, University
  of Salzburg, Hellbrunnerstr. 34, A-5020 Salzburg, Austria

Bibliografia

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• [12] Wojewódzka M, Kruszewski M, Iwaneñko T, Collins AR, SzumielI: Application of the comet assay for monitoring DNA damagein workers exposed to chronic low-dose irradiation. I. Strandbreakage. Mutat Res. 1998; 416 (1-2): 21-35.
• [13] Bajpayee M, Dhawan A, Parmar P, Pandey AK, Mathur N,Seth PK: Gender-related differences in basal DNA damage inlymphocytes of a healthy Indian population using the alkalineComet assay. Mutat Res. 2002; 520 (1-2): 83–91.
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Identyfikatory

DOI

10.1515/bimo-2016-0001