The multiple quantitative similarities of basic frequencies, harmonics, magnetic field intensities, voltages, band widths, and energetic solutions that define the Schumann resonances within the separation between the earth and ionosphere and the activity within the human cerebral cortices suggest the capacity for direct interaction. The recent experimental demonstration of the representations of the Schumann resonances within the spectral densities of normal human quantitative electroencephalographic (QEEG) activity suggests a casual interaction. Calculations supported by correlations between amplitudes of the global Schumann resonances measured several thousands of km away (which were nearly identical to our local measurements) and the coherence and current densities or these frequency bands between cerebral hemispheres for a large population of human QEEG measures indicate that such interaction occurs. The energies are within the range that would allow information to be exchanged between cerebral and Schumann sources. The near-identical solution for current density from the increasing human population and background vertical electric fields suggests that changes in the former might determine the degree of coherence between the Schumann resonances. Direct comparisons of local Schumann measurements and brain activity exhibited powerful intermittent coherence within the first three harmonics. Implications of the contributions of solar transients, surface temperature, and rapidly developing technologies to modify the ionosphere‟s Schumann properties are considered.