The article presents an analysis of the need to introduce pro-ecological solutions at the fuel sector of industry, resulting from dynamic economic development, and environment protection requirements. The forecasts on the number of vehicles in the world and the subsequent growth of interest in alternative fuels are presented. The advantages of using these fuels as compared to petroleum fuels and electricity are described. The presented analysis emphasizes the context of EU legislation on environmental requirements. At the same time, it was pointed out the need to obtain the required technical and energy characteristics of alternative fuels, the competitive costs of their production, and important environmental aspects. Taking into account these premises and the principle of circular economy closed circuit, alternative fuels from organic waste, in particular from enormous amounts of organic non-biodegradable wastes (packaging, multi-material fabric, rubber, tires) were proposed. It has been shown that thermal decomposition by thermolysis, described briefly in the article, can be a method suitable for a wide economic application within the alternative fuel production system. Based on literature data and own experience, it has been found that the quality of fuels (oil, gas) obtained from the thermal decomposition of organic and mixed waste is not different from the requirements for the best quality raw materials used in the production of petrol and may even exceed the properties of petroleum. Introduction of the system of regional production and distribution of alternative fuels from waste could be remarkable driver of small towns and rural areas revitalization and development, while supporting build up and improvement of local communities.