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1
100%
Oceanologia
2001 No. 43 (2) 257-261
EN The antimicrobial activity of twelve preparations of humic substances isolated from sea water, marine bottom sediments and lake water was examined. Humic substances from marine bottom sediment samples were fractionated into humic and/or fulvic acids. The susceptibility of 11 strains of anaerobic, 8 [...]
2
88%
Polish Journal of Chemistry
1998 Vol. 72, nr 12 2537-2540
EN A 29-peptide, [ Pen(3,10,16,20,22,28) ] CMTI-III, an analogue of Cucurbita maxima trypsin inhibitor from squash seeds was synthesized by the solid phase method using the Fmoc chemistry. The inhibitory activity of the analogue, as measured by the association equilibrium constant (K-a) with bovine bet[...]
3
76%
Polish Journal of Chemistry
1998 Vol. 72, nr 9 2098-2102
EN Statherin is a 43-amino acid residue phosphominiprotein present in human parotid and submandibular saliva. It may take part in transport of calcium and phosphate and most probably is partly responsible for the protection and recalcification of tooth enamel. The solid phase synthesis of statherin and[...]
4
76%
Polish Journal of Chemistry
2001 Vol. 75, nr 12 1863-1868
EN Three peptides with sequences related to the binding loop of Cucurbita maxima trypsin inhibitor III were obtained: [G3,GIO]CMTI-HI (1-10) (1), [A1,G3,A9,G10]MTlII (1-10) (2) and c(K-A-A-P-R-I-L-M-K-Y-A-E) (3). All peptides were synthesized by the solid-phase methodusing the Fmoc/Bu t procedure. Pept[...]
5
76%
Polish Journal of Chemistry
EN Three polypeptide fragments of Hepatitis C virus protein (130-140)C, (133-142)C and (1406-1415)NS3 were synthesized using the solid-phase method. The immunogenicity of the peptides was tested on rabbits. All the peptides studied revealed homoral and cell response.
6
76%
Oceanologia
1999 No. 41 (4) 573-587
EN Extracts from seawater and sediment pore water samples were characterised by capillary electrophoresis (CE). Siderophores of the ferrioxamine family were identified. Ferrioxamine E is the dominant siderophore in both seawater and sediment pore water samples from different regions of the Baltic Sea. [...]
7
64%
Polish Journal of Chemistry
1998 Vol. 72, nr 11 2394-2398
EN Proline-rich protein (PRP), isolated from ovine colostrum, possesses strong immunotropic activity. The nonapeptide (Val-Glu-Ser-Tyr-Val-Pro-Leu-Phe-Pro) and the hexapeptide (Tyr-Val-Pro-Leu-Phe-Pro) PRP fragments reveled biological activity similar to that of the native protein. Seeking for analogue[...]
8
64%
Polish Journal of Chemistry
EN Proline-rich polypeptide fragments settled on a hexapeptide constructed od L-lysine and glycine residues were synthesized by the solid phase method: X-Lys(X)-Gly-Lys(X)-Gly-Lys(X)-Gly-OH, X= Tyr-Val-Pro-Leu-Phe-Pro and Y-Lys(Y)-Gly-Lys(Y)-Gly-Lys(Y)-Gly-OH, Y=Val-Glu-Ser-Tyr-Val-Pro-Leu-Phe-Pro. Imu[...]
9
64%
Polish Journal of Chemistry
EN New analogues of proline-rich protein (PRP) fragment were synthezed by the solid phase method using Boc/Bzl procedure. Dimer of the nonapeptide as well as dimer, trimer and tetramer of hexapeptide fragments of PRP possesing immunotropic activity were obtained.
10
64%
Polish Journal of Chemistry
1998 Vol. 72, nr 6 1017-1020
EN The 29-42 fragment of human heat shock protein 70 (hsp 70) was synthesized by the solid phase method. As determined by enzyme-linked immunosorbent assay (ELISA), the synthetic hsp 70(29-42) peptide generated relatively strong immune response in immunized rabbits. Antibody titers were comparable with[...]
11
64%
Polish Journal of Chemistry
1999 Vol. 73, nr 11 1803-1809
12
64%
Polish Journal of Chemistry
1999 Vol. 73, nr 10 1697-1710
EN These peptides were designed based on the immunoregulatory activity of linear peptides obtained after chymotrypsin digestion of PRP. Despite the fact that the structures of both analogues cannot be interpreted in terms of a single conformation, the superposition of the most populated conformations o[...]
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