The diagnosis of Parkinson’s disease (PD) is important in neurological pathology for appropriate medical therapy. Algorithms based on decision tree induction (DTI) have been widely used for diagnosing PD through biomedical voice disorders. However, DTI for PD diagnosis is based on a greedy search algorithm which causes overfitting and inferior solutions. This paper improved the performance of DTI using evolutionary-based genetic algorithms. The goal was to combine evolutionary techniques, namely, a genetic algorithm (GA) and genetic programming (GP), with a decision tree algorithm (J48) to improve the classification performance. The developed model was applied to a real biomedical dataset for the diagnosis of PD. The results showed that the accuracy of the J48, was improved from 80.51% to 89.23% and to 90.76% using the GA and GP, respectively.
Data mining is the upcoming research area to solve various problems. Classification and finding association are two main steps in the field of data mining. In this paper, we use three classification algorithms: J48 (an open source Java implementation of C4.5 algorithm), Multilayer Perceptron - MLP (a modification of the standard linear perceptron) and Naïve Bayes (based on Bayes rule and a set of conditional independence assumptions) of the Weka interface. These classifiers have been used to choose the best algorithm based on the conditions of the voice disorders database. To find association rules over transactional medical database first we use apriori algorithm for frequent item set mining. These two initial steps of analysis will help to create the medical knowledgebase. The ultimate goal is to build a model, which can improve the way to read and interpret the existing data in medical database and future data as well.
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