Four chiral macrocyclic bissulfonamides derived from D-mannitol and L-threitol, possessing C2 symmetry, were obtained by a macrocyclization reaction under high-dilution conditions. Their applications for alkali metal binding processes were studied using ESI-MS technique.
Several macrocyclic diamides have been tested as ligands for complexation of alkali metal cations. Electrospray ionization mass spectrometry was found to be a perfect tool for investigation of host-guest interaction between ligands and cations studied. Effect of the ring size and regioisomerism of the amido groups on complexation properties of ligands were also investigated.
Properties of four amide-type ionophores towards binding of alkali metal cations (K+, Na+, Li+) have been established by determining the respective complex stability constants with the use of the liquid membrane ion-selective electrodes (ISEs).
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