The paper presents research concerning the influence of computational domain discretization on the results of CFD analysis. Tetrahedral and polyhedral numerical mesh types are analyzed and the mesh convergence index is calculated. The obtained results are compared to the experimental measurements concerning the estimation of drag coefficient of the vehicle model. The research carried out indicates the great influence of pre-processing on the reliability of the obtained results. Moreover, the advantages of polyhedral mesh over tetrahedral mesh are pointed out in the paper.