The field experiment was carried out in 2004-2006 in Chlebówko localized 20 km from Stargard Szczeciński and 5 km north-east from Stara Dąbrowa commune - 53°27’N and 15°10’E. The area is elevated 62-72 m above mean se level (ASL). The influence of irrigation, tillage system, and NPK mineral nutrition on weed infestation of faba bean variety ‘Titus’ with determined development rate, was evaluated. The weed infestation degree in the faba bean plantation depended on moisture conditions, fertilization rates, and tillage system. Irrigation increased the number, fresh weight, and dry matter of weeds, respectively by 92%, 130%, and 138%. Likewise, increasing nutrition elevated values of these parameters by 46%, 80%, and 95%. The tillage simplifications enhanced the weed population, particularly on irrigated and fertilized objects. Irrigation, mineral nutrition, and simplified tillage caused compensation of spring, winter and perennial weed species on plantation of faba bean ‘Titus’. Chenopodium album, Stellaria media, and Polygonum convolvulus predominated on studied plots.