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Graphene based porous coatings with antibacterial and antithrombogenous function - Materials and design

Wybrane pełne teksty z tego czasopisma
Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The studies considered graphene-based biomaterials dedicated for cardiovascular therapy. Reduced graphene oxide flakes were introduced into the porous structure of the polyelectrolyte based coatings. TEM analysis showed the presence of graphene flakes arranged parallel to the substrate surface, firmly connected to the porous coating. Biomaterials were subjected to a comprehensive diagnosis of the biological and material properties. The material behavior was simulated using finite element method. The coatings were deposited using layer by layer method. Mechanical analysis was done using Berkovich indenter geometry. They confirmed theoretical FEA based calculations, it was observed the coating stiffness incensement under the influence of introduced particles of graphene. The endanger of the bacteriology film formation was verified based on the E-coli and Staphylo coccus bacteria. Blood–material interaction was examined in the dynamic flow conditions. Bacteriological analysis showed reduced presence of bacteria after contact with the surface with introduced graphene flakes. Dynamic analyzes on blood showed high activation of the coagulation, strong platelets consumption and a strong immune response. It is caused by sharp edge of the single plane of the graphene flake.
Rocznik
Strony
540--549
Opis fizyczny
Bibliogr. 39 poz., rys., tab., wykr.
Twórcy
autor
  • Institute of Metallurgy and Materials Science Polish Academy of Sciences, 25 Reymonta Street, 30-059 Cracow, Poland, r.major@imim.pl
autor
  • Department of Medicine, Jagiellonian University Medical College, 8 Skawinska Street, 31-066 Cracow, Poland
autor
  • Institute of Metallurgy and Materials Science Polish Academy of Sciences, 25 Reymonta Street, 30-059 Cracow, Poland
autor
  • Institute of Electronic Materials Technology, 133 Wolczynska Street, 01-919 Warsaw, Poland
autor
  • AGH University of Science and Technology, Faculty of Mechanical Engineering and Robotics, Al. Mickiewicza 30, 30-059 Cracow, Poland
autor
  • Czestochowa University of Technology, Faculty of Civil Engineering, 69 Dabrowskiego Street, 42-201 Czestochowa, Poland
autor
  • Laboratoire des Matériaux et du Génie Physique Grenoble Institute of Technology – Minatec 3, Parvis Louis Néel, BP 257 38016 Grenoble Cedex 1, France
autor
  • Institute of Metallurgy and Materials Science Polish Academy of Sciences, 25 Reymonta Street, 30-059 Cracow, Poland
Bibliografia
  • [1] V. Singh, D. Joung, L. Zhai, S. Das, S.I. Khondaker, S. Seal, Graphene based materials: past, present and future, Progress in Materials Science 56 (2011) 1178–1271.
  • [2] O. Akhavan, E. Ghaderi, H. Emamy, F. Akhavan, Genotoxicity of graphene nanoribbons in human mesenchymal stem cells, Carbon (2013) 419–431.
  • [3] O. Akhavan, M. Choobtashani, E. Ghaderi, Protein degradation and RNA efflux of viruses photocatalyzed by graphene tungsten oxide composite under visible light irradiation, Journal of Physical Chemistry C 116 (2012) 9653–9659.
  • [4] O. Akhavan, E. Ghaderi, Toxicity of graphene and graphene oxide nanowalls against bacteria, ACS Nano 4 (2010) 5731–5736.
  • [5] W. Hu, C. Peng, W. Luo, M. Lv, X. Li, D. Li, Graphene-based antibacterial paper, ACS Nano 4 (2010) 4317–4323.
  • [6] O. Akhavan, E. Ghaderi, Escherichia coli bacteria reduce graphene oxide to bactericidal graphene in a self-limiting manner, Carbon 50 (2012) 1853–1860.
  • [7] J. Ma, J. Zhang, Z. Xiong, Y. Yong, X.S. Zhao, Preparation, characterization and antibacterial properties of silver modified graphene oxide, Journal of Materials Chemistry 21 (2011) 3350–3352.
  • [8] O. Akhavan, E. Ghaderi, Photocatalytic reduction of graphene oxide nanosheets on TiO2 thin film for photoinactivation of bacteria in solar light irradiation, Journal of Physical Chemistry C 113 (2009) 20214–20220.
  • [9] O. Akhavan, E. Ghaderi, K. Rahimi, Adverse effects of graphene incorporated in TiO2 photocatalyst on minuscule animals under solar light irradiation, Journal of Materials Chemistry 22 (2012) 23260–23266.
  • [10] N. Mohanty, V. Berry, Graphene-based single-bacterium resolution biodevice and DNA transistor: interfacing graphene derivatives with nanoscale and microscale biocomponents, Nano Letters 8 (2008) 4469–4476.
  • [11] O. Akhavan, E. Ghaderi, R. Rahighi, Toward single-DNA electrochemical biosensing by graphene nanowalls, ACS Nano 6 (2012) 2904–2916.
  • [12] Y. Shao, J. Wang, H. Wu, J. Liu, I.A. Aksay, Y. Lin, Graphene based electrochemical sensors and biosensors: a review, Electroanalysis 22 (2010) 1027–1036.
  • [13] K. Yang, S. Zhang, G. Zhang, X. Sun, S.T. Lee, Z. Liu, Graphene in mice. Ultrahigh in vivo tumor uptake and efficient photothermal therapy, Nano Letters 10 (2010) 3318–3323.
  • [14] J.T. Robinson, S.M. Tabakman, Y. Liang, H. Wang, H. Sanchez Casalongue, D. Vinh, Ultrasmall reduced graphene oxide with high near-infrared absorbance for photothermal therapy, Journal of the American Chemical Society 133 (2011) 6825–6831.
  • [15] O. Akhavan, E. Ghaderi, H. Emamy, Nontoxic concentrations of PEGylated graphene nanoribbons for selective cancer cell imaging and photothermal therapy, Journal of Materials Chemistry 22 (2012) 20626–20633.
  • [16] W. Zhang, Z. Guo, D. Huang, Z. Liu, X. Guo, H. Zhong, Synergistic effect of chemo-photothermal therapy using PEGylated graphene oxide, Biomaterials 32 (2011) 8555–8561.
  • [17] Z.M. Markovic, L.M. Harhaji-Trajkovic, B.M. Todorovic- Markovic, D.P. Kepic, K.M. Arsikin, S.P. Jovanovic, In vitro comparison of the photothermal anticancer activity of graphene nanoparticles and carbon nanotubes, Biomaterials 32 (2011) 1121–1129.
  • [18] O. Akhavan, E. Ghaderi, S. Aghayee, Y. Fereydooni, A. Talebi, The use of a glucose-reduced graphene oxide suspension for photothermal cancer therapy, Journal of Materials Chemistry 22 (2012) 13773–13781.
  • [19] X. Sun, Z. Liu, K. Welsher, J.T. Robinson, A. Goodwin, S. Zaric, Nano-graphene oxide for cellular imaging and drug delivery, Nano Research 1 (2008) 203–212.
  • [20] Z. Liu, J.T. Robinson, X. Sun, H. Dai, PEGylated nanographene oxide for delivery of water-insoluble cancer drugs, Journal of the American Chemical Society 130 (2008) 10876–10877.
  • [21] L. Zhang, J. Xia, Q. Zhao, L. Liu, Z. Zhang, Functional graphene oxide as a nanocarrier for controlled loading and targeted delivery of mixed anticancer drugs, Small 6 (2010) 537–544.
  • [22] S. Park, N. Mohanty, J. Suk, A. Nagaraja, J. An, R.D. Piner, Biocompatible, robust free-standing paper composed of a TWEEN/graphene composite, Advanced Materials 22 (2010) 1736–1740.
  • [23] S. Agarwal, X. Zhou, F. Ye, Q. He, G.C.K. Chen, J. Soo, Interfacing live cells with nanocarbon substrates, Langmuir 26 (2010) 2244–2247.
  • [24] N. Li, X. Zhang, Q. Song, R. Su, Q. Zhang, T. Kong, The promotion of neurite sprouting and outgrowth of mouse hippocampal cells in culture by graphene substrates, Biomaterials 32 (2011) 9374–9382.
  • [25] B. Yin, W. Wang, Y. Jin, The application of component mode synthesis for the dynamic analysis of complex structures using ADINA, Computers and Structures 5/6 (1997) 931–938.
  • [26] K.J. Bathe, J. Walczak, H. Zhang, Some recent advances for practical finite element analysis, in: Proceedings of the 9th ADINA Conference, 1993, pp. 511–521.
  • [27] D. Ma, K. Xu, J. He, Numerical simulation for determining the mechanical properties of thin metal films using depth-sensing indentation technique, Thin Solid Films 323 (1998) 183–187.
  • [28] X. Cai, H. Bangert, Finite-element analysis of the interface on hardness measurements of thin films, Surface and Coatings Technology 81 (1996) 240–255.
  • [29] C. Picart, B. Senger, K. Sengupta, F. Dubreuil, A. Fery, Measuring mechanical properties of polyelectrolyte multilayer thin films: novel methods based on AFM and optical techniques, Colloids and Surfaces A: Physicochemical and Engineering Aspects 303 (2007) 30–36.
  • [30] R. Major, Self-assembling surfaces of blood-contacting materials, Journal of Materials Science: Materials in Medicine 24 (2013) 725–733.
  • [31] Sheng, O. Junfei, L. Zhangpeng, Y. Shengrong, W. Jinqing, Layer-by-layer assembly and tribological property of multilayer ultrathin films constructed by modified graphene sheets and polyethyleneimine, Applied Surface Science 258 (2012) 2231–2236.
  • [32] M. Kot, Ł. Major, J. Lackner, W. Rakowski, Enhancement of mechanical and tribological properties of Ti/TiN multilayers over TiN single layer, Journal of Balkan Tribological Association 18 (2012) 92–105.
  • [33] J.M. Lackner, Ł. Major, M. Kot, Microscale interpretation of tribological phenomena in Ti–TiN soft-hard multilayer coatings on soft austenite steel substrates, Bulletin of the Polish Academy of Sciences: Technical Sciences 59/3 (2011) 343–355.
  • [34] M. Kot, T. Moskalewicz, B. Wendler, W. Rakowski, A. Czyrska- Filemonowicz, Micromechanical and tribological properties of nc-TiC/a-C nanocomposite coatings, Solid State Phenomena 177 (2011) 36–46.
  • [35] B. Major, W. Mróz, M. Jelinek, R. Kosydar, M. Kot, Ł. Major, S. Burdyńska, R. Kustosz, BN-based nano-composites obtained by pulsed laser deposition, Bulletin of the Polish Academy of Sciences: Technical Sciences 54/2 (2006) 181–188.
  • [36] M. Kot, W. Rakowski, Ł. Major, J. Lackner, Analysis of spherical indentation of coating-substrate systems – indentation experiments and FEM modeling, Materials and Design 43 (2013) 99–111.
  • [37] R. Major, P. Lacki, Finite element modeling of thin films deposited on the polyurethane substrate, Archives of Metallurgy and Materials 50 (2005) 379–385.
  • [38] R. Major, P. Lacki, J.M. Lackner, B. Major, Modelling of nanoindentation to simulate thin layer behaviour, Bulletin of the Polish Academy of Sciences: Technical Sciences 54 (2006) 189–198.
  • [39] B. Major, R. Major, F. Bruckert, J.M. Lackner, R. Ebner, R. Kustosz, P. Lacki, New gradient coatings on TiN and TiCN basis for biomedical application to blood contact, Advances in Materials Science 7 (2007) 63–70.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-ce0a1aa8-2075-430a-9fef-92a420cba05b
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