Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Tytuł artykułu

Metody selekcji mikroorganizmów o właściwościach probiotycznych

Warianty tytułu
Methods of selection of probiotic microorganisms
Języki publikacji
Wzrost zapadalności na choroby cywilizacyjne zwiększa zapotrzebowanie na żywność funkcjonalną, której zadaniem jest wspomaganie zdrowia człowieka. Prozdrowotne działanie probiotyków przejawia się zapobieganiem, zmniejszaniem częstotliwości występowania lub łagodzeniem przebiegu niektórych schorzeń związanych z układem pokarmowym i odpornościowym. W artykule omówiono kategorie i metody selekcji szczepów probiotycznych na podstawie zalecenia WHO/FAO z 2001 r. oraz najnowsze ustalenia środowiska naukowego specjalizującego się w tej dziedzinie.
Increased incidence of civilization diseases increases public demand for functional foods. Beneficial effects of probiotics on human health are displayed by prevention, decreasing occurrence and soothing outcome of several illnesses associated with gastrointestinal tract and immune responses. This review discusses probiotic strains' selection categories and techniques according to WHO/ FAO guidelines from 2001 and the latest improvements proposed by probiotic scientific community.
Opis fizyczny
Bibliogr. 31 poz.
  • Laboratorium Bezpieczeństwa i Właściwości Prozdrowotnych Żywności, Katedra Biotechnologii i Mikrobiologii Żywności, Uniwersytet Przyrodniczy w Poznaniu
  • 1. Barc MC, Charrin-Sarnel C, Rochet V, Bourlioux F, Sandré C, Boureau H, Doré J, Collignon A. (2008) Molecular analysis of the digestive microbiota in a gnotobiotic mouse model during antibiotic treatment: Influence of Saccharomyces boulardii. Anaerobe 14:229-233.
  • 2. Barlow M. (2009) What antimicrobial resistance has taught us about horizontal gene transfer. Methods Mol Biol. 532:397-411.
  • 3. Cai Y, Matsumoto M, Benno Y. (2000) Bifidobacterium lactis Meile et al. 1997 is a subjective synonym of Bifidobacterium animalis (Mitsuoka 1969) Scardovi and Trovatelli 1974. Microbiol Immunol. 44:815-820.
  • 4. Coconnier MH, Liévin V, Lorrot M, Servin AL. (2000) Antagonistic activity of Lactobacillus acidophilus LB against intracellular Salmonella enterica serovar Typhimurium infecting human enterocyte-like Caco-2/TC-7 cells. Appl Environ Microbiol 66:1152-1157.
  • 5. De Baets L, Van Iwaarden P, Meeus N, Schimmel H, Philipp W, Emons H. (2009) First certified reference materials for molecular fingerprinting of two approved probiotic Bacillus strains. Int J Food Microbiol. 129:16-20.
  • 6. De Vos WM, Hugenholtz J. (2004) Engineering metabolic highways in Lactococci and other lactic acid bacteria. Trends Biotechnol. 22:72-79.
  • 7. De Vrese M, Schrezenmeir J. (2008) Probiotics, prebiotics, and synbiotics. Adv Biochem Eng Biotechnol. 111:1-66.
  • 8. European Food Safety Authority (2007) Introduction of a Qualified Presumption of Safety (QPS) approach for assessment of selected microorganisms referred to EFSA. The EFSA Journal 587:1-16.
  • 9. Favier CF, Vaughan EE, De Vos WM, Akkermans AD. (2002) Molecular monitoring of succession of bacterial communities in human neonates. Appl Environ Microbiol. 68:219-226.
  • 10. Gueimonde M, Salminen S. (2006) New methods for selecting and evaluating probiotics, Digestive and Liver Disease 38:S242-S247.
  • 11. Huis in't Veld JH, Havenaar R, Marteau P. (1994) Establishing a scientific basis for probiotic R&D. Trends Biotechnol. 12:6-8.
  • 12. Joint FAO/WHO Working Group Report on Drafting Guidelines for the Evaluation of Probiotics in Food London, Ontario, Canada, April 30 and May 1, 2002.
  • 13. Lactic acid and its ammonium, calcium, potassium and sodium salts. W: Seventeenth Report of the Joint FAO/WHO Expert Committee on Food Additives, Wld Hlth Org. techn. Rep. Ser., 1974, No. 539; FAO Nutrition Meetings Report Series, 1974, No. 53. (
  • 14. Lahtinen SJ, Ahokoski H, Reinikainen JP, Gueimonde M, Nurmi J, Ouwehand AC, Salminen SJ. (2008) Degradation of 16S rRNA and attributes of viability of viable but nonculturable probiotic bacteria.Lett Appl Microbiol. 46:693-698.
  • 15. Lahtinen SJ, Gueimonde M, Ouwehand AC, Reinikainen JP, Salminen SJ. (2006) Comparison of four methods to enumerate probiotic bifidobacteria in a fermented food product. Food Microbiol. 23:571-577.
  • 16. Lin CK, Tsai HC, Lin PP, Tsen HY, Tsai CC. (2008) Lactobacillus acidophilus LAP5 able to inhibit the Salmonella choleraesuis invasion to the human Caco-2 epithelial cell. Anaerobe 14:251-255.
  • 17. Liong MT. (2008) Safety of probiotics: translocation and infection. Nutr Rev. 66:192-202.
  • 18. Mackie RI, Sghir A, Gaskins HR. (1999) Developmental microbial ecology of the neonatal gastrointestinal tract. Am J Clin Nutr. 69:1035S-1045S.
  • 19. Matsuki T, Watanabe K, Fujimoto J, Kado Y, Takada T, Matsumoto K, Tanaka R. (2004) Quantitative PCR with 16S rRNA-gene-targeted species-specific primers for analysis of human intestinal bifidobacteria. Appl Environ Microbiol. 70:167-173.
  • 20. Meile L, Ludwig W, Rueger U, Gut C, Kaufmann P, Dasen G, Wenger S, Teuber M. (1997) Bifidobacterium lactis sp. nov., a moderately oxygen tolerant species isolated from fermented milk. Syst Appl Microbiol 20:57-64.
  • 21. Mogensen G, Salminen S, O'Brien J, Ouwehand AC, Holzapfel W, Shortt C, Fonden R, Miller GD, Donohue D, Playne M, Crittenden R, Salvadori B, Zink R. (2002) Inventory of microorganisms with a documented history of safe use in food. Bull Int Dairy Fed. 377:10-19.
  • 22. Molin G, Jeppsson B, Johansson ML, Ahrné S, Nobaek S, Stahl M, Bengmark S. (1993) Numerical taxonomy of Lactobacillus spp. associated with healthy and diseased mucosa of the human intestines. J Appl Bacteriol. 74:314-323.
  • 23. Prasad J, Gill H, Smart j, Gopal PK. (1998) Selection and Characterisation of Lactobacillus and Bifidobacterium strains for use as probiotics. Int Dairy J. 8:993-1002.
  • 24. Ross RP, Morgan S, Hill C. (2002) Preservation and fermentation: past, present and future. Int J Food Microbiol. 79:3-16.
  • 25. Saavedra J, Bauman N, Oung I, Perman J, Yolken R. (1994) Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhea and shedding of rotavirus. Lancet 47:709-710.
  • 26. Salminen S, Gorbach S, Lee YK, Benno Y. (2004) Human Studes on Probiotics: What Is Scientifically Proven Today?. W: Lactic Acid Bacteria: Microbiology and functional aspects. Third Edition, Revised and Expanded, (Red.) Salminen S, von Wright A, Ouwehand A, Marcel Dekker Inc., New York USA, str. 515-530.
  • 27. Sanders ME. (2006) Summary of Probiotic Activities of Bifidobacterium lactis HN019. J Clin Gastroenterol. 40:776-783.
  • 28. Sanders ME, Huis in't Veld J. (1999) Bringing a probiotic-containing functional food to the market: microbiological, product, regulatory and labeling issues. Antonie van Leeuwenhoek 76:293-315.
  • 29. Savjani JK, Gajjar AK, Savjani KT. (2009) Mechanisms of resistance: useful tool to design antibacterial agents for drug - resistant bacteria. Mini Rev Med Chem. 9:194-205.
  • 30. Standard for infant formula and formulas for special medical purposes intended for infants. CODEX STAN 72 - 1981 (
  • 31. Zourvalin P. (2006) Antibiotic resistance: the pros and cons of probiotics. Dig Liver Dis. 38:S261-265
Typ dokumentu
Identyfikator YADDA
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.