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Low Power, High Dynamic Range Analogue Multiplexer for Multi-Channel Parallel Recording of Neuronal Signals Using Multi-Electrode Arrays

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Abstrakty
EN
In the paper we present the design and test resultsof an integrated circuit combining a sample & hold circuit andan analogue multiplexer. The circuit has been designed as abuilding block for a multi-channel Application Specific IntegratedCircuit (ASIC) for recording signals from alive neuronal tissueusing high-density micro-electrode arrays (MEAs). The designis optimised with respect to critical requirements for suchapplications, i.e. short sampling time, low power dissipation, goodl inearity and high dynamic range. Presented design comprisessample&hold circuits with class AB operational amplifier, novelshift register, which allows minimising cross-coupling of the clocksignal and control logic. The circuit has been designed in 0.35µm CMOS process and has been successfully implemented in aprototype multi-channel ASIC.
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  • Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, al. Mickiewicza 30, 30-059 Cracow, Poland, prydygier@fatcat.ftj.agh.edu.pl
Bibliografia
  • [1] A. M. Litke et al., “What does the eye tell the brain? development of a system for the large-scale recording of retinal output activity,” IEEE Transactions on Nuclear Science, vol. 51, no. 4, pp. 1434-1440, August 2004.
  • [2] K. D. Wise et al., “Microelectrodes, Microelectronics, and Implantable Neural Microsystems,” Proceedings of the IEEE, vol. 96, no. 7, pp. 1184-1202, 2008.
  • [3] S. Xu, S. K. Talwar, E. S. Hawley, L. Li, and J. K. Chapin, “A multichannel telemetry system for brain microstimulation in freely roaming animals,” J. Neuroscience Methods, vol. 133, pp. 57-63, 2004.
  • [4] W. Dąbrowski, P. Gryboś, and A. M. Litke, “A low noise multichannel integrated circuit for recording neuronal signal using microelectrode arrays,” J. Neuroscience Methods, vol. 133, pp. 57-63, 2004.
  • [5] W. Dąbrowski et al., “Development of front-end ASICs for imaging neuronal activity in live tissue,” Nuclear Instruments and Methods in Physics Research, vol. A541, pp. 405-411, 2005.
  • [6] P. Hottowy, W. Dąbrowski, and A. Skoczeń, “A multichannel ASIC for Stimulation of live Neural Tissue - Analysis of Stimulation Artifacts and Design Considerations,” in Proceedings of the 12th International Conference MIXDES 2005, Krakow, Poland, 2005, pp. 591-596.
  • [7] P. Hottowy et al., “A MEA-based System for Multichannel, Low Artifact Stimulation and Recording of Neural Activity,” in Proceedings of the 6th International Meeting on Substrate- Integrated Micro Electrodes Arrays, Reutlingen, Germany, 2008, pp. 259-262.
  • [8] I. Obeid, M. A. L. Nicolelis, and P. D. Wolf, “A multichannel telemetry system for single unit neural recordings,” J. Neuroscience Methods, vol. 133, pp. 33-38, 2004.
  • [9] P. Rydygier, T. Fiutowski, and W. Dąbrowski, “Design of a Low Noise, Low Power, High Dynamic Range Amplifier-Filter Circuit for Recording Neural Signals Using Multielectrode Arrays,” in Proceedings of the 16th International Conference MIXDES 2009, Lodz, Poland, 2009, pp. 242-247.
  • [10] J. Kaplon, “Fast, Low Power, Analogue Multiplexer for Readout of Multichannel Electronics,” CERN report, CERN/ECP 95-11, 08 June 1995.
  • [11] R. Gregorian, Introduction to CMOS Op-Amps and Comparators, 1st ed. New York: Wiley Interscience Publication, 1999.
  • [12] D. M. Monticelli, “A Quad CMOS Single-Supply Op Amp with Railto-Rail Output Swing,” IEEE Journal of Solid-State Circuits, vol. sc-21, no. 6, pp. 1026-1034, 1986.
  • [13] R. Hogervorst et al., “A Compact Power-Efficient 3V CMOS Rail-to-Rail Input/Output Operational Amplifier for VLSI Cell Libraries,” IEEE Journal of Solid-State Circuits, vol. 29, no. 12, pp. 1505-1513, 1994.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-article-BWA0-0046-0027
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