Języki publikacji
Abstrakty
To decrease friction factor and enhance the biocompatibility of medical devices manufactured from poly(vinyl chloride), PVC, the surface modification with wear resistant polyurethane/polyvinylpyrrolidone (PUR/PVP) hydrogel coating can be applied. In the present work substrates were dip-coated with PVP and PUR solutions and thermally cured. The variable process parameters were: solvent system; concentration of polymers (1, 2 or 3% w/v); coating baths temperature (22, 38 and 55°C); drying temperature (32, 50 and 67°C); length of break between process steps (5, 30 and 90 s); and solutions storage time (up to 72 hrs). The quality of coatings was determined by friction coefficients against porcine aorta, weights of the deposited layer and the swelling capacity. The solvent system and polymers concentration were crucial factors. The increased temperature of coating solutions caused increased deposition but decreased durability. The most lubricious samples were dried in 50oC. Coatings from the solutions prepared 24h prior to use had better properties than those from fresh solutions.
Czasopismo
Rocznik
Tom
Strony
38--45
Opis fizyczny
Bibliogr. 15 poz., rys., tab.
Twórcy
autor
autor
autor
- Warsaw University of Technology, The Faculty of Chemical and Process Engineering, ul. Warynskiego 1, 00-645 Warszawa, Poland,, e-mail: T.Ciach@ichip.pw.edu.pl
Bibliografia
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- 13. KaŸmierska, K., Szwast, M. & Ciach, T. (2008). Determination of urethral catheter surface lubricity. J. Mater. Sci. Mater. Med. 19(6), 2301 – 2306. DOI: 10.1007/s10856-007-3339-4.
- 14. KaŸmierska, K. A., Kuc, K. & Ciach, T. (2008). Polyvinylpyrrolidone-polyurethane interpolymer hydrogel coating as a local drug delivery system. Acta Pol. Pharm. 65(6), 763 – 766. Retrieved January 28, 2010, from http://www.ptfarm.pl/pub/File/acta_pol_2008/6_2008/763-766.pdf.
- 15. D'Errico, G., De Lellis, M., Mangiapia, G., Tedeschi, A., Ortona, O., Fusco, S., Borzacchiello, A. & Ambrosio, L. (2008). Structural and mechanical properties of UV-photocross-linked poly(N-vinyl-2-pyrrolidone) hydrogels. Biomacromolecules 9(1), 231 – 240. DOI: 10.1021/bm7008137
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