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http://yadda.icm.edu.pl:80/baztech/element/bwmeta1.element.baztech-7df329a1-af11-4127-bb49-1b6d1deca7bd

Czasopismo

Acta of Bioengineering and Biomechanics

Tytuł artykułu

Hemodynamic impacts of left coronary stenosis : a patient-specific analysis

Autorzy Chaichana, T.  Sun, Z.  Jewkes, J. 
Treść / Zawartość
Warianty tytułu
Języki publikacji EN
Abstrakty
EN This study analyses the hemodynamic variations surrounding stenoses located at the left coronary bifurcation, and their influence on the wall shear stress (WSS) in realistic coronary geometries. Four patients with suspected coronary artery disease were chosen, and coronary models were reconstructed based on high-resolution CT data. The coronary stenoses were observed at the left circumflex and left anterior descending branches, resulting in a lumen narrowing of >50%. Flow analysis was performed using computational fluid dynamics, to simulate the cardiac flow conditions of the realistic individual patient geometry. Blood flow and WSS changes in the left coronary artery were calculated throughout the entire cardiac phases. Our results revealed that the recirculation regions were found at the poststenotic locations. WSS was found to increase at the stenotic positions in all four patients. There is a strong correlation between coronary stenosis and the hemodynamic changes, which are reflected in blood flow pattern and WSS, based on the realistic left coronary geometries.
Słowa kluczowe
PL tętnica wieńcowa   dynamika cieczy   naprężenie  
EN coronary artery disease   computational fluid dynamics (CFD)   wall shear stress  
Wydawca Oficyna Wydawnicza Politechniki Wrocławskiej
Czasopismo Acta of Bioengineering and Biomechanics
Rocznik 2013
Tom Vol. 15, nr 3
Strony 107--111
Opis fizyczny BIbliogr. 24 poz., rys., tab.
Twórcy
autor Chaichana, T.
  • Discipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University, Perth, Western Australia, Australia
autor Sun, Z.
  • Discipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University, Perth, Western Australia, Australia, z.sun@curtin.edu.au
autor Jewkes, J.
  • Fluid Dynamics Research Group, Department of Mechanical Engineering, Curtin University, Perth, Western Australia, Australia
Bibliografia
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